Rat IgG Fc fragment

Products_type

Native Protein
Products_short_name

[IgG Fc fragment]
Products_name_syn

[fragment crystallizable region]
Purity

>=95% (SDS-PAGE)
Form

Liquid
Storage_stability

Aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze / thaw cycles.
Tested_application

ELISA (EIA), Western Blot (WB)
About

Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name

Rattus norvegicus

Gene target

-
Gene symbol

FCGBP, FCGR1A, FCRLB
Short name

IgG Fc
Technique

IgG, FC, IgGs
Host

Rat serum IgG digested with papain
Isotype

IgG, Antibody fragments and scFv fragments, single chain variable fragments can be E. coli expressed. Fragment peptides for polyclonals give monoclonal like antibodies as the epitope is very small. IgG Fc and(ab)2 fragments are small and stable subunits of the antibody obtained by enzymatic digestion. Complement fragments, bp DNA fragments are common. IgG
Species

Rat, Rats
Alternative name

Rat Immunoglobulin G fragment c fragment
Alternative technique

immunoglobulins

Identity

HGNC:3613
Gene

FCGR1A
Long gene name

Fc gamma receptor Ia
Synonyms gene name
- Fc fragment of IgG, high affinity Ia, receptor for (CD64)
- Fc fragment of IgG, high affinity Ia, receptor (CD64)
- Fc fragment of IgG receptor Ia
Synonyms
- CD64
- CD64A
- FcgammaRI
- FcgammaRIa
- FCG1
- FCGR1
Synonyms name
- Fc gamma RI
GenBank acession
- BC032634
Locus

1q21.2
Discovery year

1992-12-03
Entrez gene record

2209
Pubmed identfication
- 8697799
- 9763663
RefSeq identity
- NM_000566
Classification
- CD molecules
- Immunoglobulin like domain containing
VEGA ID

OTTHUMG00000012089
Locus Specific Databases
- FCGR1Abase: Mutation registry for CD64 deficiency
- LRG_59