Rat Anti-Mouse MHC Class II-APC

Products_type

Antibody
Products_short_name

[MHC Class IIC]
Products_name_syn

[I-A antigen]
Clone

[NIMR-4]
Reactivity

Mouse
Specificity

Mouse MHC Class II
Form

Supplied in PBS/NaN3 and a stabilizing agent
Concentration

0.1 mg/mL
Storage_stability

Store at 2-8 degree C.
Tested_application

Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) Formalin, Immunocytochemistry (ICC)
Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
Latin name

Mus musculus, Rattus norvegicus
About

Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.

Gene target

MHC Class II-APC
Gene symbol

APC, SPINK2, CRABP2, MGST2, IBSP, APOL2, MGAT2, P4HA2, XYLT2, TMED10P1
Short name

Anti-Mouse MHC Class II-APC
Technique

anti-, Mouse, anti, antibody to, antibodies, mouses
Host

Rat
Isotype

IgG2bkappa
Label

APC
Species

Mouse, Mouses, Rats
Alternative name

Rat Antibody toMouse Major histocompabitility complex Class II-adenomatous polyposis coli
Alternative technique

murine, antibodies
Alternative to gene target

adenomatous polyposis coli, BTPS2 and DP2 and DP2.5 and DP3 and GS and PPP1R46, APC and IDBG-37007 and ENSG00000134982 and 324, microtubule plus-end binding, nuclei, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT.25770 and IDBG-644937 and ENSBTAG00000018852 and 533233

Identity

HGNC:583
Gene

APC
Long gene name

APC regulator of WNT signaling pathway
Synonyms gene name
- adenomatosis polyposis coli
- adenomatous polyposis coli
- APC, WNT signaling pathway regulator
Synonyms
- DP2
- DP3
- DP2.5
- PPP1R46
Synonyms name
- protein phosphatase 1, regulatory subunit 46
GenBank acession
- M74088
Locus

5q22.2
Discovery year

1986-01-01
Entrez gene record

324
Pubmed identfication
- 1651563
RefSeq identity
- NM_000038
Classification
- Protein phosphatase 1 regulatory subunits
- Armadillo repeat containing
VEGA ID

OTTHUMG00000128806
Locus Specific Databases

Identity

HGNC:11245
Gene

SPINK2
Long gene name

serine peptidase inhibitor Kazal type 2
Synonyms gene name
- serine protease inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
Synonyms
- HUSI-II
Synonyms name
- acrosin-trypsin inhibitor
GenBank acession
- BC022514
Locus

4q12
Discovery year

1993-12-01
Entrez gene record

6691
Pubmed identfication
- 8428671
RefSeq identity
- NM_021114
Classification
- Serine peptidase inhibitors, Kazal type
VEGA ID

OTTHUMG00000128769

Identity

HGNC:7045
Gene

MGAT2
Long gene name

alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
Synonyms gene name
- mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Synonyms
- GNT-II
GenBank acession
- U15128
Locus

14q21.3
Discovery year

1993-02-16
Entrez gene record

4247
Pubmed identfication
- 7635144
RefSeq identity
- NM_002408
Classification
- Mannosyl-glycoprotein N-acetylglucosaminyltransferases
VEGA ID

OTTHUMG00000140271
Locus Specific Databases
- Congenital Disorder of Glycosylation pages

Identity

HGNC:8547
Gene

P4HA2
Long gene name

prolyl 4-hydroxylase subunit alpha 2
Synonyms gene name
- procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide II
- prolyl 4-hydroxylase, alpha polypeptide II
Synonyms
- C-P4Halpha(II)
Synonyms name
- 4-PH alpha 2
- collagen prolyl 4-hydroxylase alpha(II)
GenBank acession
- U90441
Locus

5q31.1
Discovery year

1999-02-23
Entrez gene record

8974
Pubmed identfication
- 9211872
- 9149945
RefSeq identity
- NM_004199
Classification
- MicroRNA protein coding host genes
VEGA ID

OTTHUMG00000059647

Identity

HGNC:30754
Gene

TMED10P1
Long gene name

transmembrane p24 trafficking protein 10 pseudogene 1
Synonyms gene
- TMED10P
Synonyms gene name
- transmembrane emp24-like trafficking protein 10 (yeast) pseudogene
- transmembrane emp24-like trafficking protein 10 (yeast) pseudogene 1
Synonyms
- Tmp21-II
GenBank acession
- AJ004914
Locus

8q24.3
Discovery year

2005-08-26
Entrez gene record

286102
Pubmed identfication
- 10376215
RefSeq identity
- XR_002807
VEGA ID

OTTHUMG00000165203

Name

Blotting, Western
Concept

Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data