Rat Anti-Human GM-CSF-UNLB

• Catalog number
  MBS670024
• Price
  Please ask
• Size
  0.5 mg

• Products_type
  Antibody
• Products_short_name
  [GM-CSF]
• Products_name_syn
  [Rat Anti-Human GM-CSF - Purified, Unlabeled Antibody; Rat Anti-Human GM-CSF]
• Other_names
  [GM-CSF; Granulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony-stimulating factor; CSF; molgramostin; sargramostim; OTTHUMP00000065962; granulocyte-macrophage colony stimulating factor; colony stimulating factor 2 (granulocyte-macrophage); Colony-stimulating factor; CSF; Molgramostin; Sargramostim]
• Other_gene_names
  [CSF2; CSF2; GMCSF; MGC131935; MGC138897; GMCSF]
• Clonality
  Monoclonal
• Clone
  [BVD2-23B6]
• Reactivity
  Human
• Specificity
  Human granulocyte/macrophage - colony stimulating factor (GM-CSF)1-4 (This is a neutralizing antibody)
• Form
  Purified (UNLB) Antibody
• Storage_stability
  The purified (UNLB) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. The low endotoxin, azide-free (LE/AF) antibody is supplied as 0.5 mg purified immunoglobulin in 1.0 mL of PBS. Aliquot and store at or below -20 degree C. Protect conjugated forms from light. Aliquot and freeze the low endotoxin, azide-free product at -20 degree C immediately upon receipt. Each reagent is stable for the period shown on the bottle label if stored as directed.
• Tested_application
  ELISA; Immunoprecipitation; Western Blot
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Test
  MyBioSource supplies antibodies that are for research of human proteins.
• Gene
  Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, NK cells, endothelial cells and fibroblasts that functions as a cytokine. The pharmaceutical analogs of naturally occurring GM-CSF are called sargramostim and molgramostim. Reconstitution It is recommended that sterile ddH2O containing at least 0.1% human serum albumin or bovine serum albumin be added to the vial to prepare a stock solution of not less than 1 mg/mL of the cytokine.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
• Latin name
  Rattus norvegicus

• Gene target
  GM-CSF-UNLB  
• Gene symbol
  CSF2, PPP1R3A, CSF1, CSF3, IL3
• Short name
  Anti- GM-CSF-UNLB
• Technique
  anti-Human, anti-, anti, antibody to, antibodies, antibodies against human proteins
• Host
  Rat
• Isotype
  Rat IgG2a kappa
• Species
  Human, Humans, Rats
• Alternative name
  Rat Antibody toHuman GM-CSF-UNLB
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:2434
• Gene
  CSF2
• Long gene name
  colony stimulating factor 2
• Synonyms gene name
  • colony stimulating factor 2 (granulocyte-macrophage)
• Synonyms
  • GM-CSF
  • GMCSF
• Synonyms name
  • sargramostim
  • molgramostim
  • granulocyte-macrophage colony stimulating factor
• GenBank acession
  • M11734
• Locus
  5q31.1
• Discovery year
  2001-06-22
• Entrez gene record
  1437
• Pubmed identfication
  • 3898082
  • 2999978
• RefSeq identity
  • NM_000758
• VEGA ID
  OTTHUMG00000059637

Gene info

• Identity
  HGNC:9291
• Gene
  PPP1R3A
• Long gene name
  protein phosphatase 1 regulatory subunit 3A
• Synonyms gene
  • PPP1R3
• Synonyms gene name
  • protein phosphatase 1, regulatory (inhibitor) subunit 3A (glycogen and sarcoplasmic reticulum binding subunit, skeletal muscle)
  • protein phosphatase 1, regulatory (inhibitor) subunit 3A
  • protein phosphatase 1, regulatory subunit 3A
• Synonyms
  • GM
• Synonyms name
  • glycogen-associated regulatory subunit of protein phosphatase-1
  • protein phosphatase 1 regulatory subunit GM
• GenBank acession
  • AF024578
• Locus
  7q31.1
• Discovery year
  1993-01-22
• Entrez gene record
  5506
• Pubmed identfication
  • 7926294
• RefSeq identity
  • NM_002711
• Classification
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000156944

Gene info

• Identity
  HGNC:2432
• Gene
  CSF1
• Long gene name
  colony stimulating factor 1
• Synonyms gene name
  • colony stimulating factor 1 (macrophage)
• Synonyms
  • M-CSF
  • MCSF
  • MGC31930
• Synonyms name
  • macrophage colony stimulating factor 1
• GenBank acession
  • BC021117
• Locus
  1p13.3
• Discovery year
  1986-01-01
• Entrez gene record
  1435
• Pubmed identfication
  • 1540160
• RefSeq identity
  • NM_000757
• VEGA ID
  OTTHUMG00000011646

Gene info

• Identity
  HGNC:2438
• Gene
  CSF3
• Long gene name
  colony stimulating factor 3
• Synonyms gene
  • GCSF
  • G-CSF
  • C17orf33
• Synonyms gene name
  • chromosome 17 open reading frame 33
  • colony stimulating factor 3 (granulocyte)
• Synonyms
  • MGC45931
• Synonyms name
  • granulocyte colony stimulating factor
  • pluripoietin
  • filgrastim
  • lenograstim
• Locus
  17q21.1
• Discovery year
  2001-06-22
• Entrez gene record
  1440
• Pubmed identfication
  • 3499671
  • 3501046
• RefSeq identity
  • NM_172220
• Classification
  • Receptor ligands
• VEGA ID
  OTTHUMG00000133247

Gene info

• Identity
  HGNC:6011
• Gene
  IL3
• Long gene name
  interleukin 3
• Synonyms gene name
  • interleukin 3 (colony-stimulating factor, multiple)
• Synonyms
  • IL-3
  • MULTI-CSF
  • MCGF
  • MGC79398
  • MGC79399
• Synonyms name
  • multilineage-colony-stimulating factor
  • hematopoietic growth factor
  • P-cell stimulating factor
  • mast-cell growth factor
  • colony-stimulating factor, multiple
• GenBank acession
  • M14743
• Locus
  5q31.1
• Discovery year
  2001-06-22
• Entrez gene record
  3562
• Pubmed identfication
  • 3489530
• RefSeq identity
  • NM_000588
• Classification
  • Interleukins
• VEGA ID
  OTTHUMG00000059640

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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