RAIDD (RIP-associated ICH-1, CED-3-homologous protein with DD, CRADD, Caspase and RIP adapter with DD)

• Catalog number
  MBS600966
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [RAIDD]
• Products_name_syn
  [Anti -RAIDD (RIP-associated ICH-1, CED-3-homologous protein with DD, CRADD, Caspase and RIP adapter with DD)]
• Clonality
  Monoclonal
• Clone
  [6D721]
• Reactivity
  Human
• Specificity
  Recognizes human RAIDD
• Purity
  Highly Purified Purified from concentrated hybridoma tissue culture supernatant. 95% (SDS-PAGE)
• Form
  Liquid. Purified antibody in PBS containing 0.02% sodium azide.
• Storage_stability
  -20 degree C
• Tested_application
  Western Blot (WB), Immunoprecipitation (IP)
• Description
  Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.

• Gene target
  RAIDD   RIP-associated   ICH-1   CED-3-homologous   protein   with   CRADD   Caspase   RIP   adapter   with  
• Gene symbol
  RIPK1, KRR1, AGFG1, RPAIN, RALBP1, MPRIP, CRADD, ELMO3, ELMO1, CASP2
• Short name
  RAIDD (RIP-associated ICH-1, CED-3-homologous protein with DD, CRADD, Caspase RIP adapter with DD)
• Host
  Mouse
• Isotype
  IgG1
• Alternative name
  RAIDD (RIP-associated ICH-1, CED-3-homologous protein including DD, CASP2 and receptor (TNFRSF)-interacting serine-threonine kinase 1 domain containing adaptor including death domain, caspase and RIP adapter including DD)
• Alternative to gene target
  CASP2 and RIPK1 domain containing adaptor with death domain, MRT34 and RAIDD, CRADD and IDBG-51368 and ENSG00000169372 and 8738, protein binding, nuclei, Cradd and IDBG-187068 and ENSMUSG00000045867 and 12905, CRADD and IDBG-630849 and ENSBTAG00000005107 and 615788

Gene info

• Identity
  HGNC:10019
• Gene
  RIPK1
• Long gene name
  receptor interacting serine/threonine kinase 1
• Synonyms gene name
  • receptor (TNFRSF)-interacting serine-threonine kinase 1
• Synonyms
  • RIP
• Synonyms name
  • receptor-interacting protein kinase 1
• GenBank acession
  • U25994
• Locus
  6p25.2
• Discovery year
  1999-05-07
• Entrez gene record
  8737
• Pubmed identfication
  • 7538908
  • 8612133
• RefSeq identity
  • NM_003804
• Classification
  • Ripoptosome
• VEGA ID
  OTTHUMG00000014134

Gene info

• Identity
  HGNC:5176
• Gene
  KRR1
• Long gene name
  KRR1 small subunit processome component homolog
• Synonyms gene
  • HRB2
• Synonyms gene name
  • HIV-1 rev binding protein 2
  • KRR1, small subunit (SSU) processome component, homolog (yeast)
  • KRR1, small subunit processome component homolog
• Synonyms
  • RIP-1
• GenBank acession
  • U55766
• Locus
  12q21.2
• Discovery year
  1999-12-09
• Entrez gene record
  11103
• Pubmed identfication
  • 7505766
  • 11027267
  • 11359931
  • 8675026
• RefSeq identity
  • NM_007043
• Classification
  • SSU processome
• VEGA ID
  OTTHUMG00000169759

Gene info

• Identity
  HGNC:5175
• Gene
  AGFG1
• Long gene name
  ArfGAP with FG repeats 1
• Synonyms gene
  • HRB
• Synonyms gene name
  • HIV-1 Rev binding protein
• Synonyms
  • RIP
  • RAB
• Locus
  2q36.3
• Discovery year
  1996-11-15
• Entrez gene record
  3267
• Pubmed identfication
  • 7637788
• RefSeq identity
  • NM_004504
• Classification
  • ArfGAPs
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000133186

Gene info

• Identity
  HGNC:28641
• Gene
  RPAIN
• Long gene name
  RPA interacting protein
• Synonyms
  • MGC4189
  • RIP
  • hRIP
• GenBank acession
  • AY775314
• Locus
  17p13.2
• Discovery year
  2006-05-08
• Entrez gene record
  84268
• Pubmed identfication
  • 16135809
  • 16008515
• RefSeq identity
  • NM_001033002
• VEGA ID
  OTTHUMG00000177872

Gene info

• Identity
  HGNC:9841
• Gene
  RALBP1
• Long gene name
  ralA binding protein 1
• Synonyms
  • RLIP76
  • RIP1
  • RIP
• GenBank acession
  • L42542
• Locus
  18p11.22
• Discovery year
  2000-02-11
• Entrez gene record
  10928
• Pubmed identfication
  • 7673236
• RefSeq identity
  • NM_006788
• VEGA ID
  OTTHUMG00000131596

Gene info

• Identity
  HGNC:30321
• Gene
  MPRIP
• Long gene name
  myosin phosphatase Rho interacting protein
• Synonyms
  • RHOIP3
  • M-RIP
  • p116Rip
• Synonyms name
  • Rho interacting protein 3
• GenBank acession
  • BC014102
• Locus
  17p11.2
• Discovery year
  2008-06-02
• Entrez gene record
  23164
• Pubmed identfication
  • 10048485
• RefSeq identity
  • NM_015134
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000059276

Gene info

• Identity
  HGNC:2340
• Gene
  CRADD
• Long gene name
  CASP2 and RIPK1 domain containing adaptor with death domain
• Synonyms
  • RAIDD
• Synonyms name
  • RIP-associated ICH1/CED3-homologous protein with death domain
• GenBank acession
  • U84388
• Locus
  12q22
• Discovery year
  1999-05-07
• Entrez gene record
  8738
• Pubmed identfication
  • 8985253
  • 9044836
• RefSeq identity
  • NM_003805
• Classification
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000170322

Gene info

• Identity
  HGNC:17289
• Gene
  ELMO3
• Long gene name
  engulfment and cell motility 3
• Synonyms gene name
  • engulfment and cell motility 3 (ced-12 homolog, C. elegans)
• Synonyms
  • FLJ13824
  • CED12
  • ELMO-3
  • CED-12
• Locus
  16q22.1
• Discovery year
  2001-12-13
• Entrez gene record
  79767
• Pubmed identfication
  • 11595183
• RefSeq identity
  • NM_024712
• Classification
  • Engulfment and cell motility proteins
• VEGA ID
  OTTHUMG00000133570

Gene info

• Identity
  HGNC:16286
• Gene
  ELMO1
• Long gene name
  engulfment and cell motility 1
• Synonyms gene name
  • engulfment and cell motility 1 (ced-12 homolog, C. elegans)
• Synonyms
  • KIAA0281
  • CED12
  • ELMO-1
  • CED-12
• GenBank acession
  • AF398885
• Locus
  7p14.2-p14.1
• Discovery year
  2001-12-13
• Entrez gene record
  9844
• Pubmed identfication
  • 11595183
• RefSeq identity
  • NM_130442
• Classification
  • Engulfment and cell motility proteins
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000023701

Gene info

• Identity
  HGNC:1503
• Gene
  CASP2
• Long gene name
  caspase 2
• Synonyms gene
  • NEDD2
• Synonyms gene name
  • neural precursor cell expressed, developmentally down-regulated 2
  • caspase 2, apoptosis-related cysteine peptidase
• Synonyms
  • ICH1
  • PPP1R57
  • MGC2181
• Synonyms name
  • protein phosphatase 1, regulatory subunit 57
• GenBank acession
  • AK096245
  • BC002427
  • BM998653
  • BX537669
  • CB988674
  • U13021
• Locus
  7q34
• Discovery year
  1994-01-21
• Entrez gene record
  835
• Pubmed identfication
  • 7789948
  • 8780721
  • 19075813
• RefSeq identity
  • NM_032982
• Classification
  • Caspases
  • Caspase recruitment domain containing
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000023641

MeSH Data

• Name
  Models, Chemical
• Concept
  Scope note: Theoretical representations that simulate the behavior or activity of chemical processes or phenomena; includes the use of mathematical equations, computers, and other electronic equipment.
• Tree numbers
  • E05.599.495

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