Rabbit Polyclonal to Rat TH / Tyrosine Hydroxylase
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Catalog number
MBS242059
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Price
Please ask
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Size
0.05 mL
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Products_type
Antibody
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Products_short_name
[TH / Tyrosine Hydroxylase]
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Products_name_syn
[TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase ]
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Other_names
[tyrosine 3-monooxygenase isoform b; Tyrosine 3-monooxygenase; tyrosine 3-monooxygenase; dystonia 14; tyrosine 3-hydroxylase; tyrosine hydroxylase; Tyrosine 3-hydroxylase; TH]
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Products_gene_name
[TH]
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Other_gene_names
[TH; TH; TYH; DYT14; DYT5b; TYH; TH]
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Clonality
Polyclonal
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Reactivity
Human, Rat
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Specificity
Specific for the ~60k tyrosine hydroxylase protein phosphorylated at Ser40. Some higher molecular weight bands may be detected by the antibody depending upon the brain region being studied, protein loads and the detection methods used. The antibody has three orders of magnitude selectivity over dephospho TH.
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Purity
Immunoaffinity purified
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Form
10mM HEPES, pH 7.5, 150 mM NaCl, 0.1 mg/mL BSA, 50% Glycerol
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Storage_stability
Short term: -20°C; Long term: -80°C.
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Tested_application
Immunohistochemistry (IHC), Immunofluorescence (IF), Western Blot (WB)
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long. Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin name
Oryctolagus cuniculus, Rattus norvegicus
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Gene target
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Gene symbol
TH
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Short name
Rabbit Polyclonal TH / Tyrosine Hydroxylase
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Technique
Polyclonal, Rabbit, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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Host
Rabbit, Rabbits
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Species
Rat, Rats
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Alternative name
production species: rabbit polyclonal to Rat TH / Tyrosine Hydroxylase
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Alternative technique
polyclonals, rabbit-anti
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Gene info
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Identity
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Gene
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Long gene name
tyrosine hydroxylase
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1986-01-01
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Entrez gene record
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RefSeq identity
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VEGA ID
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Locus Specific Databases
Product images
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