Rabbit Polyclonal to Human STEAP1 / STEAP
-
Catalog number
MBS242245
-
Price
Please ask
-
Size
0.05 mg
-
-
Products_type
Antibody
-
Products_short_name
[STEAP1 / STEAP]
-
Products_name_syn
[Anti-STEAP1 / STEAP Antibody (C-Terminus) IHC-plus; STEAP1; Metalloreductase STEAP1; PRSS24; STEAP; Human STEAP1; STEAP]
-
Other_names
[metalloreductase STEAP1; Metalloreductase STEAP1; metalloreductase STEAP1; six-transmembrane epithelial antigen of prostate 1; six transmembrane epithelial antigen of the prostate 1; Six-transmembrane epithelial antigen of prostate 1]
-
Products_gene_name
[STEAP1]
-
Products_gene_name_syn
[STEAP]
-
Other_gene_names
[STEAP1; STEAP1; STEAP; PRSS24; PRSS24; STEAP]
-
Clonality
Polyclonal
-
Reactivity
Human, Mouse, Rat
-
Specificity
Recognizes STEAP1 (six transmembrane epithelial antigen of the prostate), a 39kD protein which is a member of a family of cell surface serpentine transmembrane antigens of the prostate. STEAP1 is predominantly expressed in human prostate and is up-regulated in several cancer lines including prostate, ovarian, cervical, breast, testicular, bladder, colon and Ewing sarcoma. It is significantly expressed at cell-cell junctions and has been shown to be a target of human CD8 T cells. This indicates that it could be used as a potential target for cancer immunotherapy. This antibody does not cross-react with other STEAP-proteins
-
Purity
Affinity Purified
-
Form
PBS, 0.02% sodium azide.
-
Concentration
1 mg/ml
-
Storage_stability
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
-
Tested_application
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Group
Polyclonals and antibodies
-
About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin name
Oryctolagus cuniculus
-
Gene target
-
Gene symbol
STEAP1
-
Short name
Rabbit Polyclonal STEAP1 / STEAP
-
Technique
Polyclonal, Rabbit, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
Host
Rabbit, Rabbits
-
Species
Human, Humans
-
Alternative name
production species: rabbit polyclonal to H. sapiens STEAP1 / STEAP
-
Alternative technique
polyclonals, rabbit-anti
-
Gene info
-
Identity
-
Gene
-
Long gene name
STEAP family member 1
-
Synonyms gene
-
Synonyms gene name
- six transmembrane epithelial antigen of the prostate
- six transmembrane epithelial antigen of the prostate 1
- STEAP1 metalloreductase
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year
1999-12-10
-
Entrez gene record
-
RefSeq identity
-
Classification
- Serine proteases
- STEAP family
-
VEGA ID
Product images
Similar products