Rabbit Polyclonal to Human SMO / Smoothened

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Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Group

Polyclonals and antibodies
About

Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
Latin name

Oryctolagus cuniculus

Gene target

SMO Smoothened
Gene symbol

SMO, SMOX
Short name

Rabbit Polyclonal SMO / Smoothened
Technique

Polyclonal, Rabbit, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
Host

Rabbit, Rabbits
Species

Human, Humans
Alternative name

production species: rabbit polyclonal to H. sapiens smoothened, frizzled family receptor / Smoothened
Alternative technique

polyclonals, rabbit-anti
Alternative to gene target

smoothened, frizzled family receptor, FZD11 and Gx and SMOH, SMO and IDBG-40669 and ENSG00000128602 and 6608, Wnt-activated receptor activity, Cell surfaces, Smo and IDBG-132261 and ENSMUSG00000001761 and 319757, SMO and IDBG-635317 and ENSBTAG00000013287 and 539308

Identity

HGNC:11119
Gene

SMO
Long gene name

smoothened, frizzled class receptor
Synonyms gene
- SMOH
Synonyms gene name
- smoothened (Drosophila) homolog
- smoothened homolog (Drosophila)
- smoothened, seven transmembrane spanning receptor
- smoothened, frizzled family receptor
Synonyms
- FZD11
Synonyms name
- frizzled family member 11
GenBank acession
- U84401
Locus

7q32.1
Discovery year

1996-12-18
Entrez gene record

6608
Pubmed identfication
- 9628830
RefSeq identity
- NM_005631
Classification
- G protein-coupled receptors, Class F frizzled
VEGA ID

OTTHUMG00000158421
Locus Specific Databases
- LRG_1393