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Products_type
Antibody
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Products_short_name
[GHSR / Ghrelin Receptor]
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Products_name_syn
[Anti-GHSR / Ghrelin Receptor Antibody (Internal) IHC-plus; GHSR; GHS receptor; GH secretagogue receptor; GHRP; GHS-R; GH-releasing peptide receptor; Ghrelin receptor; Ghrp receptor; Human GHSR; Ghrelin Receptor]
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Other_names
[growth hormone secretagogue receptor type 1 isoform 1b; Growth hormone secretagogue receptor type 1; growth hormone secretagogue receptor type 1; GHRP; GHS-R; ghrelin receptor; GH-releasing peptide receptor; growth hormone secretagogue receptor; GH-releasing peptide receptor; GHRP; Ghrelin receptor]
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Products_gene_name
[GHSR]
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Other_gene_names
[GHSR; GHSR; GHS-R; GHRP]
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Clonality
Polyclonal
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Reactivity
Gibbon, Gorilla, Human, Monkey Predicted Reactivity: Mouse, Rat, Bat, Bovine, Hamster, Horse, Rabbit (at least 90% immunogen sequence identity)
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Specificity
Human Ghrelin Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
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Purity
Immunoaffinity Purified
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Form
PBS, 0.1% sodium azide.
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Concentration
1 mg/ml
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Storage_stability
Long term: -70 degree C; Short term: +4 degree C
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Tested_application
Immunohistochemistry (IHC - Paraffin)
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Description
Ghrelin, GHRL gene, obestatin prepropeptide or lenomorelin from ghrelinergic cells in the gastrointestinal tract. GHRL is a neuropeptide in the central nervous system regulating appetite. Ghrelin is regulating the distribution and rate of use of body energy. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Group
Polyclonals and antibodies
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About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
