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Products_type
Antibody
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Products_short_name
[TMEM123 / Porimin]
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Products_name_syn
[Anti-TMEM123 / Porimin Antibody (aa173-188) IHC-plus; TMEM123; KCT-3; KCT3; PORMIN; Transmembrane protein 123; Porimin; Serine/threonine-rich receptor; Human TMEM123; Porimin]
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Other_names
[porimin; Porimin; porimin; KCT-3; serine/threonine-rich receptor; pro oncosis receptor inducing membrane injury; pro-oncosis receptor inducing membrane injury; keratinocytes associated transmembrane protein 3; keratinocytes-associated transmembrane protein 3; transmembrane protein 123; Keratinocytes-associated transmembrane protein 3; KCT-3; Pro-oncosis receptor inducing membrane injury; Transmembrane protein 123]
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Products_gene_name
[TMEM123]
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Other_gene_names
[TMEM123; TMEM123; KCT3; PORMIN; PORIMIN; KCT3; KCT-3]
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Clonality
Polyclonal
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Reactivity
Gibbon, Gorilla, Human, Monkey, Rabbit Predicted Reactivity: Mouse, Rat, Hamster, Horse, Chicken (at least 90% immunogen sequence identity)
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Specificity
A synthetic peptide corresponding to amino acids 173-188 SRRGIRYRTIDEHDAI of human Porimin; GenBank no. AAG2164.1. This sequence is 100% conserved in cow, and 93% conserved in rat, mouse, and chicken.
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Purity
Protein G Purified
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Form
PBS, 0.05% sodium azide.
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Concentration
0.5 mg/ml
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Storage_stability
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Western Blot (WB)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Immunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Group
Polyclonals and antibodies
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Latin name
Oryctolagus cuniculus
