Rabbit Polyclonal (IgG) to Human LTA / TNF Beta
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Catalog numberMBS248961
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PricePlease ask
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Size0.05 mL
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Products_typeAntibody
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Products_short_name[LTA / TNF Beta]
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Products_name_syn[Anti-LTA / TNF Beta Antibody (aa17-66) IHC-plus; LTA; Lymphotoxin-alpha; LT-alpha; TNFSF1; TNF-beta; TNFB; Tumor necrosis factor beta; LT; TNF Beta; Human LTA; TNF Beta]
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Other_names[lymphotoxin-alpha; Lymphotoxin-alpha; lymphotoxin-alpha; LT-alpha; TNF-beta; TNF superfamily, member 1; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1; lymphotoxin alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1]
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Products_gene_name[LTA]
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Other_gene_names[LTA; LTA; LT; TNFB; TNFSF1; TNFB; TNFSF1; LT-alpha]
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ClonalityPolyclonal
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ReactivityHuman, Mouse, Rat
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SpecificityTNF- beta antibody detects endogenous levels of TNF- beta.
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PurityImmunoaffinity Purified
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FormPBS, pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
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Concentration1 mg/ml
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Storage_stabilityStore at -20 degree C.
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Tested_applicationImmunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutImmunoglobulin gamma, IgG, mouse monoclonal H&L chain clones or rabbit, goat polyclonal antibodies have 4 parts. There are 2 heavy chains, 2 light chains. The IgG antibody has 2 antigen binding sites. They represent 70% or more of serum antibodies. This antibody can be antigen purified or protein A or G purified. For storage sodium azide is added or you can call us to request azide free antibody preparations. These will need colder storage temperatures. Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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GroupPolyclonals and antibodies
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Latin nameOryctolagus cuniculus
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GeneTumor necrosis factor (TNFa, tumor necrosis factor alpha, TNFα, cachexin, or cachectin) is a cell signaling protein (cytokine) involved in systemic inflammation and is one of the cytokines that make up the acute phase reaction. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNFb or TNF beta also bin on TNF receptors for Th1 activation.
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Gene target
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Gene symbolTNF, TNFRSF1A, LTA, TNFRSF1B, LTBR
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Short nameRabbit Polyclonal (IgG) LTA / TNF Beta
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TechniquePolyclonal, Rabbit, IgG, IgGs, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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HostRabbit, Rabbits
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IsotypeIgG, IgG
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SpeciesHuman, Humans
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Alternative nameproduction species: rabbit polyclonal (Immunoglobulin G) to H. sapiens lymphotoxin alpha (tumor necrosis factor superfamily, member 1) / tumor necrosis factor b
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Alternative techniquepolyclonals, rabbit-anti, immunoglobulins
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Alternative to gene targettumor necrosis factor, DIF and TNF-alpha and TNFA and TNFSF2, TNF and IDBG-300259 and ENSG00000232810 and 7124, transcription regulatory region DNA binding, Extracellular, Tnf and IDBG-177358 and ENSMUSG00000024401 and 21926, TNF and IDBG-634161 and ENSBTAG00000025471 and 280943
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Gene info
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Identity
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Gene
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Long gene nametumor necrosis factor
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor (TNF superfamily, member 2)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1A
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1A
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Tumor necrosis factor receptor superfamily
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namelymphotoxin alpha
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Synonyms gene
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Synonyms gene name
- lymphotoxin alpha (TNF superfamily, member 1)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTNF receptor superfamily member 1B
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Synonyms gene
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Synonyms gene name
- tumor necrosis factor receptor superfamily, member 1B
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-01-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- CD molecules
- MicroRNA protein coding host genes
- Tumor necrosis factor receptor superfamily
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namelymphotoxin beta receptor
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Synonyms gene
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1996-03-12
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Entrez gene record
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Pubmed identfication
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Classification
- Tumor necrosis factor receptor superfamily
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VEGA ID