RABBIT ANTI Smac/DIABLO (C-TERMINAL)

• Catalog number
  MBS221639
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [SMAC/DIABLO]
• Other_names
  [diablo homolog, mitochondrial isoform 4; Diablo homolog, mitochondrial; diablo homolog, mitochondrial; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; diablo, IAP-binding mitochondrial protein; Direct IAP-binding protein with low pI; Second mitochondria-derived activator of caspase; Smac]
• Products_gene_name
  [Smac/DIABLO]
• Other_gene_names
  [DIABLO; DIABLO; SMAC; DFNA64; SMAC; Smac]
• Clonality
  Polyclonal
• Reactivity
  Mouse, Rat
• Specificity
  This item recognises the C-terminal region of human Smac/DIABLO. Inhibitors of apoptosis proteins (IAP's) block cell death by caspase inhibition. X-linked inhibitor of apoptosis (XIAP) is a member of the IAP family. Smac/DIABLO is expressed in a variety of tissues and has been identified as a negative regulator of XIAP.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 0.5 mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  Immunohistology Paraffin*, Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  Smac/DIABLO  
• Gene symbol
  DIABLO
• Short name
  RABBIT ANTI Smac/DIABLO (C-TERMINAL)
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Alternative name
  production species: rabbit antibody to Smac/diablo, IAP-binding mitochondrial protein (C-TERMINAL)
• Alternative technique
  rabbit-anti, antibodies
• Alternative to gene target
  diablo, IAP-binding mitochondrial protein, DIABLO and IDBG-62263 and ENSG00000184047 and 56616, protein binding, Plasma membranes, Diablo and IDBG-199693 and ENSMUSG00000029433 and 66593, DIABLO and IDBG-632769 and ENSBTAG00000004199 and 493999

Gene info

• Identity
  HGNC:21528
• Gene
  DIABLO
• Long gene name
  diablo IAP-binding mitochondrial protein
• Synonyms gene name
  • diablo, IAP-binding mitochondrial protein
• Synonyms
  • SMAC
  • DIABLO-S
  • FLJ25049
  • FLJ10537
  • DFNA64
• Synonyms name
  • second mitochondria-derived activator of caspase
• GenBank acession
  • AF262240
• Locus
  12q24.31
• Discovery year
  2003-10-27
• Entrez gene record
  56616
• Pubmed identfication
  • 12749848
  • 17237824
  • 21722859
• RefSeq identity
  • NM_019887
• VEGA ID
  OTTHUMG00000157014

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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