RABBIT ANTI HUMAN PTK7 (N-TERMINAL)
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Catalog number
MBS222895
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Price
Please ask
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Size
5x0.1 mg
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Products_type
Antibody
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Products_short_name
[PTK7]
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Other_names
[inactive tyrosine-protein kinase 7 isoform e; Inactive tyrosine-protein kinase 7; inactive tyrosine-protein kinase 7; PTK7 protein tyrosine kinase 7; colon carcinoma kinase 4; pseudo tyrosine kinase receptor 7; tyrosine-protein kinase-like 7; protein tyrosine kinase 7 (inactive); Colon carcinoma kinase 4; CCK-4; Protein-tyrosine kinase 7; Pseudo tyrosine kinase receptor 7; Tyrosine-protein kinase-like 7]
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Products_gene_name
[PTK7]
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Other_gene_names
[PTK7; PTK7; CCK4; CCK-4; CCK4; CCK-4]
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Clonality
Polyclonal
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Reactivity
Mouse, Rat
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Specificity
This item recognises human Protein tyrosine kinase-like 7 (PTK7), a member of the receptor tyrosine kinase family, otherwise known as Colon Carcinoma Kinase 4 (CCK4). PTK7 is highly expressed in the kidney, liver, lung, pancreas and melanocytes with weaker expression being detected in the thyroid gland, ovaries, brain, heart and skeletal muscle. PTK7 may play a role in embryonic development. It is thought to function as a cell adhesion molecule and as a novel regulator of the planar cell polarity (PCP) pathway in vertebrates. Studies also suggest that PTK7 may be involved in the tumour progression. A loss of PTK7 expression has been observed in melanoma cell lines, whereas increased levels of PTK7 have been detected in high-throughput acute myeloid leukaemia samples. In addition, PTK7 is not expressed in normal colon but has been detected in colon carcinomas and as such is a potential marker for tumour progression.
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Form
Purified Purified IgG - liquid
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Concentration
IgG concentration 1.0 mg/ml
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Storage_stability
Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
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Tested_application
Immunohistology Paraffin*, Western Blot (WB)
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
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Latin name
Oryctolagus cuniculus
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Gene target
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Gene symbol
PTK7
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Short name
RABBIT ANTI PTK7 (N-TERMINAL)
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Technique
anti human, Rabbit, anti, antibody to, anti human antibodies
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Host
Rabbit, Rabbits
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Isotype
IgG
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Species
Human, Humans
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Alternative name
production species: rabbit antibody to H. sapiens PTK7 protein tyrosine kinase 7 (N-TERMINAL)
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Alternative technique
rabbit-anti, antibodies
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Alternative to gene target
PTK7 protein tyrosine kinase 7, CCK-4 and CCK4, PTK7 and IDBG-87768 and ENSG00000112655 and 5754, transferase activity, Cell surfaces, Ptk7 and IDBG-187402 and ENSMUSG00000023972 and 71461, PTK7 and IDBG-631557 and ENSBTAG00000012761 and 514819
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Gene info
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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