RABBIT ANTI HUMAN PDCD4 (C-TERMINAL)

• Catalog number
  MBS222849
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Antibody
• Products_short_name
  [PDCD4]
• Other_names
  [programmed cell death protein 4 isoform 1; Programmed cell death protein 4; programmed cell death protein 4; neoplastic transformation inhibitor protein; nuclear antigen H731; protein 197/15a; programmed cell death 4 (neoplastic transformation inhibitor); Neoplastic transformation inhibitor protein; Nuclear antigen H731-like; Protein 197/15a]
• Products_gene_name
  [PDCD4]
• Other_gene_names
  [PDCD4; PDCD4; H731; H731]
• Clonality
  Polyclonal
• Reactivity
  Mouse (Expected from Sequence), Rat (Expected from Sequence), Xenopus (Expected from Sequence)
• Specificity
  This item detects a specific epitope within the carboxy-terminal of programmed cell death 4 (Pdcd4), a novel tumour suppressor. Pdcd4 interacts with the RNA helicase eIF4A and the scaffolding protein eIF4G, two components of the translation initiation complex, and thus inhibits protein synthesis. Pdcd4 has also been shown to inhibit transcription factor activator protein-1 (AP-1), which regulates several events required for cell invasion, including expression of matrix metalloproteinases and cell motility. Pdcd4 localizes to the nucleus in proliferating cells, and its expression is modulated by cytokines in natural killer and T cells. Pdcd4 expression is down regulated with tumour progression in carcinomas of the lung, colon, prostate and breast.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 1.0mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  ELISA (EIA), Immunohistology Paraffin*, Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  PDCD4  
• Gene symbol
  PDCD4-AS1, PDCD4
• Short name
  RABBIT ANTI PDCD4 (C-TERMINAL)
• Technique
  anti human, Rabbit, anti, antibody to, anti human antibodies
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Species
  Human, Humans
• Alternative name
  production species: rabbit antibody to H. sapiens programmed cellular death 4 (neoplastic transformation inhibitor) (C-TERMINAL)
• Alternative technique
  rabbit-anti, antibodies
• Alternative to gene target
  programmed cell death 4 (neoplastic transformation inhibitor), PDCD4 and IDBG-89535 and ENSG00000150593 and 100616113,27250, protein binding, nuclei, Pdcd4 and IDBG-176913 and ENSMUSG00000024975 and 18569, PDCD4 and IDBG-639738 and ENSBTAG00000019434 and 506724

Gene info

• Identity
  HGNC:27425
• Gene
  PDCD4-AS1
• Long gene name
  PDCD4 antisense RNA 1
• Locus
  10q25.2
• Discovery year
  2013-03-11
• Entrez gene record
  282997
• RefSeq identity
  • NR_026932
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000019045

Gene info

• Identity
  HGNC:8763
• Gene
  PDCD4
• Long gene name
  programmed cell death 4
• Synonyms gene name
  • programmed cell death 4 (neoplastic transformation inhibitor)
• Synonyms
  • H731
• Synonyms name
  • nuclear antigen H731
• GenBank acession
  • U83908
• Locus
  10q25.2
• Discovery year
  2000-05-10
• Entrez gene record
  27250
• Pubmed identfication
  • 9759869
• RefSeq identity
  • NM_014456
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000019048

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products