RABBIT ANTI HUMAN MDC

• Catalog number
  MBS221724
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [MDC]
• Other_names
  [C-C motif chemokine 22; C-C motif chemokine 22; C-C motif chemokine 22; CC chemokine STCP-1; MDC(1-69); macrophage-derived chemokine; small inducible cytokine A22; small inducible cytokine subfamily A (Cys-Cys), member 22; small-inducible cytokine A22; stimulated T cell chemotactic protein 1; stimulated T-cell chemotactic protein 1; chemokine (C-C motif) ligand 22; CC chemokine STCP-1; MDC(1-69); Macrophage-derived chemokine; Small-inducible cytokine A22; Stimulated T-cell chemotactic protein 1Cleaved into the following 3 chains:MDC(3-69); MDC(5-69); MDC(7-69)]
• Products_gene_name
  [MDC]
• Other_gene_names
  [CCL22; CCL22; MDC; ABCD-1; SCYA22; STCP-1; DC/B-CK; A-152E5.1; MDC; SCYA22]
• Clonality
  Polyclonal
• Specificity
  This item is specific for human MDC (macrophage-derived cytokine), otherwise known as CCL22, a member of the CC chemokine family expressed by macrophages, monocyte-derived dendritic cells, epithelial cells, fibroblasts and highly expressed in the thymus. MDC acts as a chemoattractant for monocytes, dendritic cells, activated T lymphocytes and NK cells, through binding to chemokine (C-C motif) receptor 4 (CCR4). CCR4 is selectively expressed by Th2 cells and several studies have revealed a link between MDC and another ligand of CCR4, known as activation-regulated chemokine (TARC/CCL17), with Th2-mediated inflammatory disorders such as atopic dermatitis.
• Form
  Purified Purified IgG - lyophilised
• Concentration
  IgG concentration 1.0mg/ml
• Storage_stability
  Prior to reconstitution store at 4 degree C. After reconstitution store at -20 degree C. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of reconstitution.
• Tested_application
  ELISA (EIA), Functional Assays (FN), Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  MDC  
• Gene symbol
  ADAM11, ADAM28, TNFAIP8, CCL22
• Short name
  RABBIT ANTI MDC
• Technique
  anti human, Rabbit, anti, antibody to, anti human antibodies
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Species
  Human, Humans
• Alternative name
  production species: rabbit antibody to H. sapiens MDC
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:189
• Gene
  ADAM11
• Long gene name
  ADAM metallopeptidase domain 11
• Synonyms gene
  • MDC
• Synonyms gene name
  • a disintegrin and metalloproteinase domain 11
• Synonyms name
  • metalloproteinase-like, disintegrin-like, cysteine-rich protein
• GenBank acession
  • D17390
• Locus
  17q21.31
• Discovery year
  1993-11-01
• Entrez gene record
  4185
• Pubmed identfication
  • 8252040
• RefSeq identity
  • NM_002390
• Classification
  • ADAM metallopeptidase domain containing
• VEGA ID
  OTTHUMG00000179038

Gene info

• Identity
  HGNC:206
• Gene
  ADAM28
• Long gene name
  ADAM metallopeptidase domain 28
• Synonyms gene name
  • a disintegrin and metalloproteinase domain 28
• Synonyms
  • eMDCII
  • MDC-Lm
  • MDC-Ls
  • ADAM23
• GenBank acession
  • AJ242015
• Locus
  8p21.2
• Discovery year
  1999-07-29
• Entrez gene record
  10863
• Pubmed identfication
  • 10794709
  • 15013428
• RefSeq identity
  • NM_021778
• Classification
  • ADAM metallopeptidase domain containing
• VEGA ID
  OTTHUMG00000163780

Gene info

• Identity
  HGNC:17260
• Gene
  TNFAIP8
• Long gene name
  TNF alpha induced protein 8
• Synonyms gene name
  • tumor necrosis factor, alpha-induced protein 8
• Synonyms
  • GG2-1
  • MDC-3.13
  • SCC-S2
• GenBank acession
  • AF070671
• Locus
  5q23.1
• Discovery year
  2004-02-11
• Entrez gene record
  25816
• Pubmed identfication
  • 10233894
  • 10644768
• RefSeq identity
  • NM_014350
• VEGA ID
  OTTHUMG00000162949

Gene info

• Identity
  HGNC:10621
• Gene
  CCL22
• Long gene name
  C-C motif chemokine ligand 22
• Synonyms gene
  • SCYA22
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 22
  • chemokine (C-C motif) ligand 22
• Synonyms
  • MDC
  • STCP-1
  • ABCD-1
  • DC/B-CK
  • A-152E5.1
  • MGC34554
• GenBank acession
  • U83171
• Locus
  16q21
• Discovery year
  1997-08-22
• Entrez gene record
  6367
• Pubmed identfication
  • 9151897
  • 9691168
• RefSeq identity
  • NM_002990
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000133454

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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