RABBIT ANTI HUMAN CD82 (C-TERMINAL)

• Catalog number
  MBS224140
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [CD82]
• Other_names
  [CD82 antigen isoform 2; CD82 antigen; CD82 antigen; C33 antigen; inducible membrane protein R2; kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4)); metastasis suppressor Kangai-1; tetraspanin-27; tspan-27; CD82 molecule; C33 antigen; IA4; Inducible membrane protein R2; Metastasis suppressor Kangai-1; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; Tspan-27; CD_antigen: CD82]
• Products_gene_name
  [CD82]
• Other_gene_names
  [CD82; CD82; R2; 4F9; C33; IA4; ST6; GR15; KAI1; SAR2; TSPAN27; KAI1; SAR2; ST6; TSPAN27; Tspan-27]
• Clonality
  Polyclonal
• Reactivity
  Mouse, Rat
• Specificity
  This item recognises the human CD82 antigen, also known as KAI1, SAR2 and TSPAN27, a multi-pass membrane protein of approximately 30kDa belonging to the tetraspanin (TM4SF) family. CD82 has been identified as a cancer metastasis suppressor protein, while ubiquitously expressed at moderate to high levels in many normal tissues, its expression is down regulated during tumour progression. Loss of CD82 and p53 is correlated with poor prognosis for patients with prostate and other forms of cancer. Research has demonstrated that CD82 interacts with CD234 (DARC). It has been hypothesized that tumour cells dislodged from the primary tumour and expressing CD82 interact with CD234 expressed on vascular cells, transmitting a senescent signal to the tumour cells. Tumour cells that have lost CD82 expression can proliferate and potentially give rise to metastases. It has been demonstrated that at least two isoforms of CD82 exist.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 1.0mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  Immunohistology Paraffin*, Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  CD82  
• Gene symbol
  CD82
• Short name
  RABBIT ANTI CD82 (C-TERMINAL)
• Technique
  anti human, Rabbit, anti, antibody to, anti human antibodies
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Species
  Human, Humans
• Alternative name
  production species: rabbit antibody to H. sapiens CD82 molecule (C-TERMINAL)
• Alternative technique
  rabbit-anti, antibodies
• Alternative to gene target
  CD82 molecule, 4F9 and C33 and GR15 and IA4 and KAI1 and R2 and SAR2 and ST6 and TSPAN27, CD82 and IDBG-40873 and ENSG00000085117 and 3732, protein binding, Plasma membranes, Cd82 and IDBG-192552 and ENSMUSG00000027215 and 12521, CD82 and IDBG-636903 and ENSBTAG00000031252 and 100335281,506713

Gene info

• Identity
  HGNC:6210
• Gene
  CD82
• Long gene name
  CD82 molecule
• Synonyms gene
  • ST6
  • KAI1
• Synonyms gene name
  • kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))
  • CD82 antigen
• Synonyms
  • R2
  • IA4
  • TSPAN27
• Synonyms name
  • suppression of tumorigenicity 6
  • R2 leukocyte antigen
• GenBank acession
  • U20770
• Locus
  11p11.2
• Discovery year
  1994-01-10
• Entrez gene record
  3732
• RefSeq identity
  • NM_002231
• Classification
  • Tetraspanins
  • CD molecules
• VEGA ID
  OTTHUMG00000166472

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