RABBIT ANTI HUMAN CD184 (N-TERMINAL)

• Catalog number
  MBS221580
• Price
  Please ask
• Size
  0.1 mg

• Products_type
  Antibody
• Products_short_name
  [CD184]
• Other_names
  [C-X-C chemokine receptor type 4 isoform a; C-X-C chemokine receptor type 4; C-X-C chemokine receptor type 4; CD184 antigen; LPS-associated protein 3; SDF-1 receptor; fusin; leukocyte-derived seven transmembrane domain receptor; lipopolysaccharide-associated protein 3; neuropeptide Y receptor Y3; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; chemokine (C-X-C motif) receptor 4; FB22; Fusin; HM89; LCR1; Leukocyte-derived seven transmembrane domain receptor; LESTR; Lipopolysaccharide-associated protein 3; LAP-3; LPS-associated protein 3; NPYRL; Stromal cell-derived factor 1 receptor; SDF-1 receptor; CD_antigen: CD184]
• Products_gene_name
  [CD184]
• Other_gene_names
  [CXCR4; CXCR4; FB22; HM89; LAP3; LCR1; NPYR; WHIM; CD184; LAP-3; LESTR; NPY3R; NPYRL; WHIMS; HSY3RR; NPYY3R; D2S201E; CXC-R4; CXCR-4; LESTR; LAP-3; LPS-associated protein 3; SDF-1 receptor]
• Clonality
  Polyclonal
• Specificity
  This item recognises the human G-protein-coupled chemokine receptor CD184 (CXCR4), a 40kDa cell surface protein known to act as a co-factor in HIV infection of CD4+ T cells. Mutations in the CD184 gene are associated with WHIM syndrome, an inherited combined immunodeficiency disease, see Taniuchi, S. et al. for details.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 0.5 mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  Immunohistology Frozen, Flow cytometry (FC/FACS), Immunoprecipitation (IP), Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  CD184  
• Gene symbol
  CXCR4
• Short name
  RABBIT ANTI CD184 (N-TERMINAL)
• Technique
  anti human, Rabbit, anti, antibody to, anti human antibodies
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Species
  Human, Humans
• Alternative name
  production species: rabbit antibody to H. sapiens CD184 (N-TERMINAL)
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:2561
• Gene
  CXCR4
• Long gene name
  C-X-C motif chemokine receptor 4
• Synonyms gene name
  • chemokine (C-X-C motif), receptor 4 (fusin)
  • chemokine (C-X-C motif) receptor 4
• Synonyms
  • LESTR
  • NPY3R
  • HM89
  • NPYY3R
  • D2S201E
  • fusin
  • HSY3RR
  • NPYR
  • CD184
• GenBank acession
  • AF005058
• Locus
  2q22.1
• Discovery year
  1998-09-17
• Entrez gene record
  7852
• Pubmed identfication
  • 9599023
  • 9379028
• Classification
  • C-X-C motif chemokine receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000153583
• Locus Specific Databases
  • CXCR4base: Mutation registry for WHIM syndrome (warts, hypogammaglobulinemia, immunodeficiency, and myelokathexis)
  • LRG_51

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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