RABBIT ANTI HUMAN ANNEXIN V

• Catalog number
  MBS223989
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [ANNEXIN V]
• Other_names
  [annexin A5; Annexin A5; annexin A5; CBP-I; PAP-I; VAC-alpha; anchorin CII; annexin V; annexin-5; calphobindin I; endonexin II; epididymis secretory protein Li 7; lipocortin V; placental anticoagulant protein 4; placental anticoagulant protein I; thromboplastin inhibitor; vascular anticoagulant-alpha; annexin A5; Anchorin CII; Annexin V; Annexin-5; Calphobindin I; CBP-I; Endonexin II; Lipocortin V; Placental anticoagulant protein 4; PP4; Placental anticoagulant protein I; PAP-I; Thromboplastin inhibitor; Vascular anticoagulant-alpha; VAC-alpha]
• Other_gene_names
  [ANXA5; ANXA5; PP4; ANX5; ENX2; RPRGL3; HEL-S-7; ANX5; ENX2; PP4; CBP-I; PP4; PAP-I; VAC-alpha]
• Clonality
  Polyclonal
• Specificity
  This item specifically recognises human Annexin V (ANXA5), otherwise known as Lipocortin V, a calcium-dependent phospholipid-binding protein and member of the annexin family, which binds with high affinity and selectivity to phosphatidylserine (PS). The translocation of PS from the cytosolic leaflet to the outer leaflet of the plasma membrane, due to a loss in plasma membrane asymmetry during apoptosis, acts as an in vivo signal for the removal of the dying cell, by phagocytosis. Detection of PS using Annexin V therefore provides a reliable tool for the indication of early programmed cell death. Annexin V has also been identified as an anticoagulant protein in the blood coagulation cascade, by acting as an inhibitor of prothrombin activation. The presence of antibodies to Annexin V, are associated with systemic lupus erythematosus (SLE), recurrent spontaneous abortions and systemic sclerosis (SSc).
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 1.0 mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 12 months from date of despatch.
• Tested_application
  ELISA (EIA), Western Blot (WB)
• Description
  This Annexin V calcium dependent phospholipid binding protein will be downstream of BCL2 pathway and at caspase apoptotic level. MyBioSource has more cell death kits and antibodies. This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  ANNEXIN  
• Gene symbol
  ANXA5
• Short name
  RABBIT ANTI ANNEXIN V
• Technique
  anti human, Rabbit, anti, antibody to, anti human antibodies
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Species
  Human, Humans
• Alternative name
  production species: rabbit antibody to H. sapiens ANNEXIN V
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:543
• Gene
  ANXA5
• Long gene name
  annexin A5
• Synonyms gene
  • ENX2
  • ANX5
• Synonyms
  • CPB-I
  • PAP-I
  • VAC-alph
  • RPRGL3
• Synonyms name
  • annexin V
  • Calphobindin I
  • Placental anticoagulant protein I
  • Vascular anticoagulant-alpha
  • endonexin II
• GenBank acession
  • U05770
• Locus
  4q27
• Discovery year
  1989-05-31
• Entrez gene record
  308
• Pubmed identfication
  • 2960376
  • 14678296
• RefSeq identity
  • NM_001154
• Classification
  • Annexins
• VEGA ID
  OTTHUMG00000133034
• Locus Specific Databases
  • LRG_606

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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