RABBIT ANTI DISC1

• Catalog number
  MBS222900
• Price
  Please ask
• Size
  5x0.1 mg

• Products_type
  Antibody
• Products_short_name
  [DISC1]
• Other_names
  [disrupted in schizophrenia 1 protein isoform Lv; Disrupted in schizophrenia 1 protein; disrupted in schizophrenia 1 protein; disrupted in schizophrenia 1]
• Products_gene_name
  [DISC1]
• Other_gene_names
  [DISC1; DISC1; SCZD9; C1orf136; KIAA0457]
• Clonality
  Polyclonal
• Reactivity
  Mouse
• Specificity
  This item recognises disrupted in schizophrenia 1 (DISC1), 93kD protein located in the nucleus, cytoplasm and mitochondria. The DISC1 protein is widely expressed in normal tissues. It is involved in neurite outgrowth and cortical development through its interaction with a variety of proteins including lissencephaly-1 (LIS1), NudeE-like (NUDEL) and phosphodiesterase 4B. In certain cases of schizophrenia the DISC1 gene has been found to be disrupted by a t(1;11) (q42.1;q14.3) translocation, and studies suggest that DISC1 could be a candidate susceptibility gene for this condition.This product has been found suitable for immunocytochemistry (ICC) at a concentration of 5ug/ml.
• Form
  Purified Purified IgG - liquid
• Concentration
  IgG concentration 1.0 mg/ml
• Storage_stability
  Store at 4 degree C or at -20 degree C if preferred. This product should be stored undiluted. Storage in frost free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of despatch.
• Tested_application
  Immunohistology Frozen, Western Blot (WB)
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• About
  Rabbits are used for polyclonal antibody production by MyBioSource. Rabbit antibodies are very stable and can be stored for several days at room temperature. MyBioSource adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
• Latin name
  Oryctolagus cuniculus

• Gene target
  DISC1  
• Gene symbol
  DISC1, TSNAX-DISC1, DISC1-IT1, DISC2
• Short name
  RABBIT ANTI DISC1
• Technique
  Rabbit, anti, antibody to
• Host
  Rabbit, Rabbits
• Isotype
  IgG
• Alternative name
  production species: rabbit antibody to DISC1
• Alternative technique
  rabbit-anti, antibodies

Gene info

• Identity
  HGNC:2888
• Gene
  DISC1
• Long gene name
  DISC1 scaffold protein
• Synonyms gene name
  • disrupted in schizophrenia 1
• GenBank acession
  • AF222980
• Locus
  1q42.2
• Discovery year
  2000-01-20
• Entrez gene record
  27185
• Pubmed identfication
  • 10814723
• RefSeq identity
  • NM_018662
• VEGA ID
  OTTHUMG00000037835

Gene info

• Identity
  HGNC:49177
• Gene
  TSNAX-DISC1
• Long gene name
  TSNAX-DISC1 readthrough (NMD candidate)
• Locus
  1q42.2
• Discovery year
  2013-09-24
• Entrez gene record
  100303453
• VEGA ID
  OTTHUMG00000183905

Gene info

• Identity
  HGNC:41325
• Gene
  DISC1-IT1
• Long gene name
  DISC1 intronic transcript 1
• Synonyms gene name
  • DISC1 intronic transcript 1 (non-protein coding)
• Locus
  1q42.2
• Discovery year
  2011-05-20
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000037834

Gene info

• Identity
  HGNC:2889
• Gene
  DISC2
• Long gene name
  disrupted in schizophrenia 2
• Synonyms gene name
  • disrupted in schizophrenia 2 (non-protein coding)
• Synonyms
  • DISC1-AS1
  • DISC1OS
  • NCRNA00015
• Synonyms name
  • DISC1 antisense RNA 1
  • non-protein coding RNA 15
• GenBank acession
  • AF222981
• Locus
  1q42.1
• Discovery year
  2000-01-20
• Entrez gene record
  27184
• Pubmed identfication
  • 10814723
  • 15478311
• RefSeq identity
  • NR_002227
• Classification
  • Long non-coding RNAs with non-systematic symbols

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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