PTC1 Mutant (CCDC6-RET), Active

Products_type

Recombinant Protein
Products_short_name

[PTC1]
Other_names

[Homo sapiens coiled-coil domain containing 6, mRNA; Coiled-coil domain-containing protein 6; coiled-coil domain-containing protein 6; coiled-coil domain containing 6; Papillary thyroid carcinoma-encoded protein; Protein H4]
Products_gene_name

[PTC1]
Products_gene_name_syn

[H4; PTC; TPC]
Other_gene_names

[CCDC6; CCDC6; H4; PTC; TPC; TST1; D10S170; D10S170; TST1]
Form

50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Storage_stability

Store product at -70 degree C.For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Tested_application

Kinase Assay, Western Blot (WB)

Gene target

PTC1 Mutant CCDC6-RET Active
Gene symbol

CCDC6, GOLGA5, RET
Short name

PTC1 Mutant (CCDC6-RET), Active
Host

Sf9 insect cells using baculovirus
Alternative name

PTC1 Mutant (CCDC6-ret proto-oncogene), functionnal
Alternative to gene target

ret proto-oncogene, CDHF12 and CDHR16 and HSCR1 and MEN2A and MEN2B and MTC1 and PTC and RET-ELE1 and RET51, RET and IDBG-71064 and ENSG00000165731 and 5979, transferase activity, Plasma membranes, Ret and IDBG-181393 and ENSMUSG00000030110 and 19713, RET and IDBG-628722 and ENSBTAG00000000570 and 515924

Identity

HGNC:18782
Gene

CCDC6
Long gene name

coiled-coil domain containing 6
Synonyms gene
- TST1
- D10S170
Synonyms gene name
- DNA segment on chromosome 10 (unique) 170
Synonyms
- PTC
- TPC
- H4
Synonyms name
- DNA segment, single copy, probe pH4 (transforming sequence, thyroid-1
GenBank acession
- S72869
Locus

10q21.2
Discovery year

2004-01-20
Entrez gene record

8030
Pubmed identfication
- 8058316
- 6745938
RefSeq identity
- NM_005436
VEGA ID

OTTHUMG00000018284

Identity

HGNC:9967
Gene

RET
Long gene name

ret proto-oncogene
Synonyms gene
- HSCR1
- MEN2A
- MTC1
- MEN2B
Synonyms gene name
- multiple endocrine neoplasia and medullary thyroid carcinoma 1
- Hirschsprung disease 1
Synonyms
- PTC
- CDHF12
- RET51
- CDHR16
Synonyms name
GenBank acession
- BC004257
Locus

10q11.21
Discovery year

1990-07-15
Entrez gene record

5979
Pubmed identfication
- 2687772
- 1611909
RefSeq identity
- NM_020975
Classification
- Cadherin related
- Receptor tyrosine kinases
VEGA ID

OTTHUMG00000018024
Locus Specific Databases
- LRG_518