Protein Tyrosine Phosphatase, Non-receptor Type Substrate 1 (PTPNS1, Macrophage Fusion Receptor, Myd-1 Antigen, SHP Substrate 1, Signal Regulatory Protein alpha2)

• Catalog number
  MBS628690
• Price
  Please ask
• Size
  0,05 mg

• Other size
  please contact us to order other different size
• Description
  Antigens are peptides or recombinant or native dependent on the production method. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Protein   Tyrosine   Phosphatase   Non-receptor   Substrate   PTPNS1   Macrophage   Receptor   Myd-1   SHP   Substrate   Signal   Regulatory   Protein   alpha2  
• Gene symbol
  NR0B2, PTPN6, PTPN11, SIRPA
• Short name
  Protein Tyrosine Phosphatase, Non-receptor Substrate 1 (PTPNS1, Macrophage Receptor, Myd-1 Antigen, SHP Substrate 1, Signal Regulatory Protein alpha2)
• Technique
  antigen, antigenes
• Alternative name
  Protein Tyrosine Phosphatase, Non-receptor classification Substrate 1 (PTPNS1, Macrophage Fusion Receptor, Myd-1 protein, SHP Substrate 1, Signal Regulatory Protein alpha2)
• Alternative technique
  antigenes

Gene info

• Identity
  HGNC:7961
• Gene
  NR0B2
• Long gene name
  nuclear receptor subfamily 0 group B member 2
• Synonyms gene name
  • nuclear receptor subfamily 0, group B, member 2
• Synonyms
  • SHP
• GenBank acession
  • AF044316
• Locus
  1p36.11
• Discovery year
  1999-08-19
• Entrez gene record
  8431
• Pubmed identfication
  • 9603951
• Classification
  • Nuclear receptor subfamily 0 group B
• VEGA ID
  OTTHUMG00000004231

Gene info

• Identity
  HGNC:9658
• Gene
  PTPN6
• Long gene name
  protein tyrosine phosphatase non-receptor type 6
• Synonyms
  • HCP
  • HCPH
  • PTP-1C
  • SHP-1
  • SHP1
• Locus
  12p13.31
• Discovery year
  1992-02-12
• Entrez gene record
  5777
• Pubmed identfication
  • 1639416
• RefSeq identity
  • NM_002831
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000168518

Gene info

• Identity
  HGNC:9644
• Gene
  PTPN11
• Long gene name
  protein tyrosine phosphatase non-receptor type 11
• Synonyms gene
  • NS1
• Synonyms gene name
  • Noonan syndrome 1
  • protein tyrosine phosphatase, non-receptor type 11
• Synonyms
  • BPTP3
  • SH-PTP2
  • SHP-2
  • PTP2C
  • SHP2
• Synonyms name
  • SH2 domain-containing protein tyrosine phosphatase 2
• GenBank acession
  • D13540
• Locus
  12q24.13
• Discovery year
  1993-03-03
• Entrez gene record
  5781
• Pubmed identfication
  • 7894486
  • 1280823
• Classification
  • Protein tyrosine phosphatases non-receptor type
  • SH2 domain containing
• VEGA ID
  OTTHUMG00000134334
• Locus Specific Databases
  • LRG_614

Gene info

• Identity
  HGNC:9662
• Gene
  SIRPA
• Long gene name
  signal regulatory protein alpha
• Synonyms gene
  • PTPNS1
• Synonyms gene name
  • protein tyrosine phosphatase, non-receptor type substrate 1
  • signal-regulatory protein alpha
• Synonyms
  • SHPS1
  • SIRP
  • MYD-1
  • BIT
  • P84
  • SHPS-1
  • SIRPalpha
  • CD172a
  • SIRPalpha2
  • MFR
  • SIRP-ALPHA-1
• GenBank acession
  • D86043
• Locus
  20p13
• Discovery year
  1999-03-19
• Entrez gene record
  140885
• Pubmed identfication
  • 9070220
  • 9062191
  • 16339511
• RefSeq identity
  • NM_080792
• Classification
  • Ig-like cell adhesion molecule family
  • C1-set domain containing
  • Signal regulatory proteins
  • V-set domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000031682

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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