PRMT5 (Protein arginine N Methyltransferase 5, Shk1 Kinase-binding Protein 1 Homolog, Jak-binding Protein 1, JBP1)

• Catalog number
  MBS616683
• Price
  Please ask
• Size
  0.2 mL

• Products_type
  Antibody
• Products_short_name
  [PRMT5]
• Products_name_syn
  [Anti -PRMT5 (Protein arginine N Methyltransferase 5, Shk1 Kinase-binding Protein 1 Homolog, Jak-binding Protein 1, JBP1)]
• Other_names
  [protein arginine N-methyltransferase 5 isoform b; Protein arginine N-methyltransferase 5; protein arginine N-methyltransferase 5; SKB1 homolog; OTTHUMP00000027922; OTTHUMP00000164558; jak-binding protein 1; 72 kDa ICln-binding protein; HMT1 hnRNP methyltransferase-like 5; shk1 kinase-binding protein 1 homolog; histone-arginine N-methyltransferase PRMT5; protein arginine methyltransferase 5; 72 kDa ICln-binding protein; Histone-arginine N-methyltransferase PRMT5 (EC:2.1.1.125); Jak-binding protein 1; Shk1 kinase-binding protein 1 homolog; SKB1 homolog; SKB1Hs]
• Other_gene_names
  [PRMT5; PRMT5; JBP1; SKB1; IBP72; SKB1Hs; HRMT1L5; HRMT1L5; IBP72; JBP1; SKB1; SKB1 homolog; SKB1Hs]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse
• Specificity
  Protein arginine methylation is an important posttranslational modification in eukaryotic cells, which has been implicated in RNA processing and trafficking, receptor-mediated signaling, and transcription. PRMT5, also known as Janus kinase-binding protein 1 (JBP1) and Skb1Hs (human homolog of Skb1 of fission yeast can catalyze the formation of omega-N(G)-monomethylarginine and symmetric omega-N(G),N(G')-dimethylarginine in a variety of proteins. Recombinant PRMT5 can mono and dimethylate histone 2A and myelin basic protein. PRMT5 appears to have lower specific enzyme activity than PRMT1.
• Purity
  Purified Purified
• Form
  Supplied as a liquid in 200ul of PBS containing 0.02% sodium azide and 0.1 mg/ml BSA.
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  Western Blot (WB)

• Gene target
  PRMT5   Protein   arginine   Methyltransferase   Shk1   Kinase-binding   Protein   Homolog   Jak-binding   Protein   JBP1  
• Gene symbol
  PRMT5-AS1, PRMT5-DT, PRMT5
• Short name
  PRMT5 (Protein arginine N Methyltransferase 5, Shk1 Kinase-binding Protein 1 Homolog, Jak-binding Protein 1, JBP1)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  PRMT5 (Protein arginine N Methyltransferase 5, Shk1 phosphorylation catalyst-binding Protein 1 Homolog, Jak-binding Protein 1, JBP1)

Gene info

• Identity
  HGNC:40533
• Gene
  PRMT5-AS1
• Long gene name
  PRMT5 antisense RNA 1
• Synonyms gene name
  • PRMT5 antisense RNA 1 (non-protein coding)
• GenBank acession
  • AK093277
• Locus
  14q11.2
• Discovery year
  2011-11-18
• Entrez gene record
  100505758
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000149898

Gene info

• Identity
  HGNC:55482
• Gene
  PRMT5-DT
• Long gene name
  PRMT5 divergent transcript
• Locus
  14q11.2
• Discovery year
  2021-03-11
• Entrez gene record
  101926933
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:10894
• Gene
  PRMT5
• Long gene name
  protein arginine methyltransferase 5
• Synonyms gene
  • HRMT1L5
  • SKB1
• Synonyms gene name
  • skb1 (S. pombe) homolog
  • SKB1 homolog (S. pombe)
• Synonyms
  • SKB1Hs
• GenBank acession
  • AF015913
• Locus
  14q11.2
• Discovery year
  1999-06-18
• Entrez gene record
  10419
• Pubmed identfication
  • 9843966
• Classification
  • 7BS protein arginine methyltranferases
• VEGA ID
  OTTHUMG00000028709

Similar products