Porcine leptin

Products_type

Active Protein
Products_short_name

[leptin]
Other_names

[leptin; Leptin; leptin; obesity factor; leptin; Obesity factor]
Other_gene_names

[Lep; Lep; OB; obese; Ob]
Purity

The purity of recombinant porcine leptin is greater than 98.0% as determined by:(a) Gel filtration analysis.(b) Analysis by reducing and non-reducing SDS-PAGE gel.(c) Gel-filtration chromatography under non denaturing conditions.
Form

White lyophilized (freeze-dried) powder.
Storage_stability

Lyophilized recombinant porcine leptin although stable at room temperature for several weeks, should be stored desiccated below -18 degree C. Upon reconstitution of recombinant porcine leptin at > 0.1 mg/ml and up to 2 mg/ml and filter sterilization recombinant porcine leptin can be stored at +4 degree C.
Gene

Human or mouse Leptin (from Greek λεπτός leptos, "thin") the "satiety hormone", is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Leptin is opposed by the actions of the hormone ghrelin, the "hunger hormone". Both hormones act on receptors in the arcuate nucleus of the hypothalamus to regulate appetite to achieve energy homeostasis. ELISA kits and peptides and antibodies are available.

Identity

HGNC:6553
Gene

LEP
Long gene name

leptin
Synonyms gene
- OBS
- OB
Synonyms gene name
- leptin (murine obesity homolog)
- leptin (obesity homolog, mouse)
Locus

7q32.1
Discovery year

1993-01-26
Entrez gene record

3952
Pubmed identfication
- 1686014
- 16932309
Classification
- Neuropeptides
VEGA ID

OTTHUMG00000157564