Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial Marker)
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Products_type
Antibody
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Products_short_name
[Podoplanin (PDPN)]
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Products_name_syn
[Aggrus; Glycoprotein 36 KD; Glycoprotein 36; gp36; GP38; GP40; HT1A1; hT1alpha1; hT1alpha2; Lung type I cell membrane associated glycoprotein; Lung type I cell membrane associated glycoprotein T1A 2; OTS8; PA2.26; Pdpn; Podoplanin; PSEC0003; PSEC0025; T1-alpha; T1A; TI1A; TIA2]
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Other_names
[podoplanin isoform c; Podoplanin; podoplanin; podoplanin; Aggrus]
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Products_gene_name
[PDPN]
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Other_gene_names
[PDPN; PDPN; T1A; GP36; GP40; Gp38; OTS8; T1A2; TI1A; T1A-2; AGGRUS; HT1A-1; PA2.26; PICD]
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Clonality
Monoclonal
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Clone
[PDPN/1433]
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Reactivity
Human. Others not known.
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Specificity
It recognizes a muco-protein of 38-43kDa, which is identified Podoplanin (PDPN). It localizes in stromal cells of peripheral lymphoid tissue and thymic epithelial cells. As a regulator of the lymphatic endothelium, podoplanin probably plays a role in maintaining the unique shape of podocytes. It is selectively expressed in lymphatic endothelium as well as lymphoangiomas, Kaposi sarcomas, and in a subset of angiosarcomas with probable lymphatic differentiation. Recent studies have also shown podoplanin to be a highly sensitive and relatively specific marker for epithelioid mesothelioma. Therefore, it can be used in a panel to distinguish mesotheliomas or mesothelial cells from pulmonary carcinomas.
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Form
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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Storage_stability
Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Tested_application
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
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Gene target
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Gene symbol
PDPN
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Short name
Podoplanin (PDPN) (Lymphatic Endothelial & Mesothelial )
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Technique
Component cell markers and DNA bp. markers are genetic markers er genes or DNA sequences with a known location on a chromosome that can be used to identify individuals or species. Protein markers in kDA.
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Host
Mouse
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Isotype
IgG1, kappa
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Alternative name
Podoplanin (podoplanin) (Lymphatic Endothelial & Mesothelial detection labelled)
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Alternative to gene target
podoplanin, AGGRUS and GP36 and Gp38 and GP40 and HT1A-1 and OTS8 and PA2.26 and T1A and T1A-2 and T1A2 and TI1A, PDPN and IDBG-90582 and ENSG00000162493 and 10630, Cell surfaces, Pdpn and IDBG-202630 and ENSMUSG00000028583 and 14726, BOVAGGRUS and IDBG-636063 and ENSBTAG00000001788 and 509732
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Gene info
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Identity
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Gene
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Long gene name
podoplanin
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
2005-07-08
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
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