PIAS2, CT (E3 SUMO-protein Ligase PIAS2, Protein Inhibitor of Activated STAT2, Protein Inhibitor of Activated STAT x, Msx-interacting Zinc Finger Protein, Miz1, DAB2-interacting Protein, DIP, Androgen Receptor-interacting Protein 3, ARIP3, PIAS-NY Protein

  • Catalog number
    MBS626028
  • Price
    Please ask
  • Size
    0.2 mL
  • Products_type
    Antibody
  • Products_short_name
    [PIAS2]
  • Products_name_syn
    [Anti -PIAS2, CT (E3 SUMO-protein Ligase PIAS2, Protein Inhibitor of Activated STAT2, Protein Inhibitor of Activated STAT x, Msx-interacting Zinc Finger Protein, Miz1, DAB2-interacting Protein, DIP, Androgen Receptor-interacting Protein 3, ARIP3, PIAS-NY Protein]
  • Other_names
    [E3 SUMO-protein ligase PIAS2 isoform X4; protein inhibitor of activated STAT, 2]
  • Other_gene_names
    [PIAS2]
  • Clonality
    Polyclonal
  • Reactivity
    Human
  • Specificity
    Recognizes human PIAS2.
  • Purity
    Affinity Purified Purified by Protein G affinity chromatography.
  • Form
    Supplied as a liquid in PBS, 0.09% sodium azide.
  • Storage_stability
    May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
  • Tested_application
    ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
  • Description
    Finger like and finger proteins are like zinc fingers small proteins with a structural motif that is characterized by the coordination of one or more zinc ions in order to stabilize the fold. Homeobox and homeodomain families. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. STAT proteins are phosphorylated by receptor related kinases and for homo or hetero dimers. JAK-STAT pathways are signaling to the nucleus of the cell.
  • Gene target
    PIAS2   SUMO-protein   Ligase   PIAS2   Protein   Inhibitor   Activated   STAT2   Protein   Inhibitor   Activated   STAT   Msx-interacting   Zinc   Finger   Protein   Miz1   DAB2-interacting   Protein   DIP   Androgen   Receptor-interacting   Protein   ARIP3   PIAS-NY   Protein  
  • Gene symbol
    PIAS2, DAB2, SUMO1, STAT2, GRAMD4, STAT6, QRICH1, SOAT1, CCDC73, ANKRD30A
  • Short name
    PIAS2, CT (E3 SUMO-protein Ligase PIAS2, Protein Inhibitor of Activated STAT2, Protein Inhibitor of Activated STAT x, Msx-interacting Zinc Finger Protein, Miz1, DAB2-interacting Protein, DIP, Androgen Receptor-interacting Protein 3, ARIP3, PIAS-NY Protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Alternative name
    PIAS2, CT (E3 SUMO-protein Ligase PIAS2, Protein suppressor on Activated signal transducer and activator on transcription 2, 113kDa, Protein suppressor on Activated Signal transducer and activation on transcription x, Msx-interacting Zinc Finger Protein, Miz1, DAB2-interacting Protein, DIP, Androgen Receptor-interacting Protein 3, ARIP3, PIAS-NY Protein
  • Alternative to gene target
    signal transducer and activator of transcription 2, 113kDa, ISGF-3 and P113 and STAT113, STAT2 and IDBG-40906 and ENSG00000170581 and 6773, identical protein binding, nuclei, Stat2 and IDBG-197036 and ENSMUSG00000040033 and 20847, STAT2 and IDBG-635999 and ENSBTAG00000004380 and 511023
Gene info
Gene info
  • Identity
    HGNC:2662
  • Gene
    DAB2
  • Long gene name
    DAB adaptor protein 2
  • Synonyms gene name
    • disabled (Drosophila) homolog 2 (mitogen-responsive phosphoprotein)
    • disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
    • Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
    • DAB2, clathrin adaptor protein
  • Synonyms
  • GenBank acession
  • Locus
    5p13.1
  • Discovery year
    1998-07-29
  • Entrez gene record
    1601
  • Pubmed identfication
  • RefSeq identity
  • VEGA ID
    OTTHUMG00000162043
Gene info
Gene info
  • Identity
    HGNC:11363
  • Gene
    STAT2
  • Long gene name
    signal transducer and activator of transcription 2
  • Synonyms gene name
    • signal transducer and activator of transcription 2, 113kD
    • signal transducer and activator of transcription 2, 113kDa
  • Synonyms
  • GenBank acession
  • Locus
    12q13.3
  • Discovery year
    1995-11-08
  • Entrez gene record
    6773
  • Pubmed identfication
  • RefSeq identity
  • Classification
    • SH2 domain containing
  • VEGA ID
    OTTHUMG00000170760
  • Locus Specific Databases
Gene info
Gene info
Gene info
Gene info
Gene info
Gene info
MeSH Data
  • Name
    Ligase Chain Reaction
  • Concept
    Scope note: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
  • Tree numbers
    • E05.393.620.311
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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Filters
PIAS2 CT E3 SUMO protein Ligase PIAS2 Protein Inhibitor of A
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