PDK1 Docking Motif, Phosphorylated (Ser/Thr) (PDPK1, PI-P3 Dependent Kinase, 3a Phosphoinositide-dependent Protein Kinase 1)

• Catalog number
  MBS601967
• Price
  Please ask
• Size
  5x0.1 mL

• Products_type
  Antibody
• Products_short_name
  [PDK1 Docking Motif]
• Products_name_syn
  [Anti -PDK1 Docking Motif, Phosphorylated (Ser/Thr) (PDPK1, PI-P3 Dependent Kinase, 3a Phosphoinositide-dependent Protein Kinase 1)]
• Clonality
  Monoclonal
• Clone
  [3i23]
• Specificity
  Recognizes phosphorylated Ser or Thr that is surrounded by Tyr or Phe at the -1 and +1 positions and Phe at the -4 position. It also recognizes peptides containing Lys instead of Phe at the -4 position. Does not crossreact with the non-phosphorylated PDK1 docking motifs or with other phosphorylated motifs. This antibody detects endogenous levels of phosphorylated proteins containing PDK1 docking motif, including phospho-Akt.
• Purity
  Ascites Ascites
• Form
  Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA,
• Storage_stability
  May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)

• Gene target
  PDK1   Docking   Motif   Phosphorylated   Ser/Thr   PDPK1   PI-P3   Dependent   Kinase   Phosphoinositide-dependent   Protein   Kinase  
• Gene symbol
  PDPK1, PDK1, SLC10A3, IPCEF1, SH3GL1P3, CYP1A2, SERPINF2, PDIA3, SERPINA1, EXOSC10
• Short name
  PDK1 Docking Motif, Phosphorylated (Ser/Thr) (PDPK1, PI-P3 Dependent Kinase, 3a Phosphoinositide-dependent Protein Kinase 1)
• Host
  Mouse
• Isotype
  IgG2a
• Alternative name
  PDK1 Docking Motif, Phosphorylated (L-serine/L-threonine) (PDPK1, PI-P3 Dependent phosphorylation catalyst, 3a Phosphoinositide-dependent Protein phosphorylation catalyst 1)

Gene info

• Identity
  HGNC:8816
• Gene
  PDPK1
• Long gene name
  3-phosphoinositide dependent protein kinase 1
• Synonyms
  • PDK1
• Synonyms name
  • PkB kinase
• GenBank acession
  • AF017995
• Locus
  16p13.3
• Discovery year
  1998-03-23
• Entrez gene record
  5170
• Pubmed identfication
  • 9094314
  • 9445477
• Classification
  • AGC family kinases
• VEGA ID
  OTTHUMG00000128874

Gene info

• Identity
  HGNC:8809
• Gene
  PDK1
• Long gene name
  pyruvate dehydrogenase kinase 1
• Synonyms gene name
  • pyruvate dehydrogenase kinase, isoenzyme 1
  • pyruvate dehydrogenase kinase, isozyme 1
• GenBank acession
  • L42450
• Locus
  2q31.1
• Discovery year
  1996-08-14
• Entrez gene record
  5163
• Pubmed identfication
  • 7499431
• RefSeq identity
  • NM_002610
• VEGA ID
  OTTHUMG00000132285

Gene info

• Identity
  HGNC:22979
• Gene
  SLC10A3
• Long gene name
  solute carrier family 10 member 3
• Synonyms gene name
  • solute carrier family 10, member 3
• Synonyms
  • P3
  • DXS253E
• GenBank acession
  • X12458
• Locus
  Xq28
• Discovery year
  2003-08-08
• Entrez gene record
  8273
• Pubmed identfication
  • 8733135
• RefSeq identity
  • NM_019848
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000013369
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:21204
• Gene
  IPCEF1
• Long gene name
  interaction protein for cytohesin exchange factors 1
• Synonyms
  • PIP3-E
  • KIAA0403
• Synonyms name
  • phosphoinositide binding protein PIP3-E
• GenBank acession
  • AB007863
• Locus
  6q25.2
• Discovery year
  2009-02-27
• Entrez gene record
  26034
• Pubmed identfication
  • 11804589
  • 19756519
• RefSeq identity
  • NM_001130699
• Classification
  • Pleckstrin homology domain containing
• VEGA ID
  OTTHUMG00000015872

Gene info

• Identity
  HGNC:10837
• Gene
  SH3GL1P3
• Long gene name
  SH3 domain containing GRB2 like 1, endophilin A2 pseudogene 3
• Synonyms gene
  • SH3GLP3
• Synonyms gene name
  • SH3-domain GRB2-like pseudogene 3
  • SH3 domain containing GRB2 like 1 pseudogene 3
• Synonyms
  • CNSA-P3
• GenBank acession
  • X99662
• Locus
  17q24.2
• Discovery year
  1996-10-26
• Entrez gene record
  727736
• Pubmed identfication
  • 9169142
• VEGA ID
  OTTHUMG00000180161

Gene info

• Identity
  HGNC:2596
• Gene
  CYP1A2
• Long gene name
  cytochrome P450 family 1 subfamily A member 2
• Synonyms gene name
  • cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 2
  • cytochrome P450, family 1, subfamily A, polypeptide 2
• Synonyms
  • P3-450
  • CP12
• GenBank acession
  • AF182274
• Locus
  15q24.1
• Discovery year
  1990-04-25
• Entrez gene record
  1544
• Pubmed identfication
  • 15128046
• RefSeq identity
  • NM_000761
• Classification
  • Cytochrome P450 family 1
• VEGA ID
  OTTHUMG00000172901
• Locus Specific Databases
  • PharmVar Human Cytochrome P450 (CYP) Allele Nomenclature
  • LRG_1274

Gene info

• Identity
  HGNC:9075
• Gene
  SERPINF2
• Long gene name
  serpin family F member 2
• Synonyms gene
  • PLI
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
• Synonyms
  • API
  • ALPHA-2-PI
  • A2AP
  • AAP
  • alpha2AP
• Synonyms name
  • alpha-2-plasmin inhibitor
  • alpha-2-antiplasmin
• GenBank acession
  • D00174
• Locus
  17p13.3
• Discovery year
  1989-04-14
• Entrez gene record
  5345
• Pubmed identfication
  • 3416655
  • 24172014
• RefSeq identity
  • NM_000934
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000090552
• Locus Specific Databases
  • LRG_885

Gene info

• Identity
  HGNC:4606
• Gene
  PDIA3
• Long gene name
  protein disulfide isomerase family A member 3
• Synonyms gene
  • GRP58
• Synonyms gene name
  • glucose regulated protein, 58kDa
  • protein disulfide isomerase-associated 3
  • protein disulfide isomerase family A, member 3
• Synonyms
  • P58
  • ERp61
  • ERp57
  • ERp60
  • GRP57
  • PI-PLC
  • HsT17083
• Locus
  15q15.3
• Discovery year
  1997-06-09
• Entrez gene record
  2923
• Pubmed identfication
  • 8974399
• RefSeq identity
  • NM_005313
• Classification
  • Protein disulfide isomerases
• VEGA ID
  OTTHUMG00000044444

Gene info

• Identity
  HGNC:8941
• Gene
  SERPINA1
• Long gene name
  serpin family A member 1
• Synonyms gene
  • PI
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
• Synonyms
  • AAT
  • A1A
  • PI1
  • alpha-1-antitrypsin
  • A1AT
  • alpha1AT
• Synonyms name
  • protease inhibitor 1
  • anti-elastase
  • alpha-1 antitrypsin
  • alpha-1 proteinase inhibitor
• GenBank acession
  • X01683
• Locus
  14q32.13
• Discovery year
  1986-01-01
• Entrez gene record
  5265
• Pubmed identfication
  • 24172014
• RefSeq identity
  • NM_001002235
• Classification
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000150355
• Locus Specific Databases
  • LRG_575

Gene info

• Identity
  HGNC:9138
• Gene
  EXOSC10
• Long gene name
  exosome component 10
• Synonyms gene
  • PMSCL2
• Synonyms gene name
  • polymyositis/scleroderma autoantigen 2, 100kDa
• Synonyms
  • PM-Scl
  • PM/Scl-100
  • Rrp6p
  • RRP6
  • p2
  • p3
  • p4
• Synonyms name
  • polymyositis/scleroderma autoantigen 2 (100kD)
• GenBank acession
  • BC073788
• Locus
  1p36.22
• Discovery year
  1994-09-19
• Entrez gene record
  5394
• Pubmed identfication
  • 1383382
  • 1644924
• RefSeq identity
  • NM_001001998
• Classification
  • Exosome complex
• VEGA ID
  OTTHUMG00000002123

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