PDGF Receptor alpha/beta, phosphorylated (Tyr849/Tyr857)

• Catalog number
  MBS601271
• Price
  Please ask
• Size
  0.1 mL

• Products_type
  Antibody
• Products_short_name
  [PDGF Receptor alpha/beta]
• Products_name_syn
  [Anti -PDGF Receptor alpha/beta, phosphorylated (Tyr849/Tyr857)]
• Clonality
  Monoclonal
• Clone
  [8A26]
• Reactivity
  Human, Mouse, Rat
• Specificity
  Recognizes endogenous levels of human PDGF receptor alpha and beta at ~190kD only when phosphorylated on Tyr849 of PDGFR alpha and Tyr857 of PDGFR beta. May crossreact with other activated tyrosine kinases. Species Crossreactivity: Mouse, rat
• Purity
  Supernatant Supernatant
• Form
  Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, < 0.02% sodium azide, 50% glycerol.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP)
• Description
  The PDGF Receptor alpha/beta, phosphorylated (Tyr849/Tyr857) is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  PDGF   Receptor   alpha/beta   phosphorylated   Tyr849/Tyr857  
• Gene symbol
  PDGFA
• Short name
  PDGF Receptor alpha/beta, phosphorylated (Tyr849/Tyr857)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  PDGF Receptor a/b, phosphorylated (Tyr849/Tyr857)

Gene info

• Identity
  HGNC:8799
• Gene
  PDGFA
• Long gene name
  platelet derived growth factor subunit A
• Synonyms gene name
  • platelet-derived growth factor alpha polypeptide
• Synonyms
  • PDGF1
  • PDGF-A
• Synonyms name
  • PDGF A-chain
  • platelet-derived growth factor alpha chain
• Locus
  7p22.3
• Discovery year
  1986-01-01
• Entrez gene record
  5154
• Pubmed identfication
  • 1505216
  • 2536956
• VEGA ID
  OTTHUMG00000151412

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