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Products_type
Antibody
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Products_short_name
[Orexin 2 Receptor]
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Products_name_syn
[Anti -Orexin 2 Receptor (Hypocretin 2 Receptor)]
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Other_names
[orexin receptor type 2; Orexin receptor type 2; orexin receptor type 2; ox2-R; ox-2-R; OTTHUMP00000017762; hypocretin receptor type 2; hypocretin (orexin) receptor 2; Hypocretin receptor type 2]
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Other_gene_names
[HCRTR2; HCRTR2; OX2R]
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Clonality
Polyclonal
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Reactivity
Rat
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Specificity
Rat is 94% homologous with mouse OX2R and 84% with canine and human. No significant homology is seen with OX1R or other G-protein-coupled receptors.
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Purity
Serum Serum
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Form
Supplied as a liquid in PBS, 40% glycerol.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
ELISA (EL/EIA), Western Blot (WB)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.