Nuclear Receptor LXR alpha, Ligand Binding Domain (NR1H3, RLD-1)[Nuclear Receptor LXR alpha, Ligand Binding Domain]

• Catalog number
  MBS602384
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human, Rat
• Description
  The Receptor LXR alpha, Ligand Binding Domain (NR1H3, RLD-1)[ Receptor LXR alpha, Ligand Binding Domain] is a α- or alpha protein sometimes glycoprotein present in blood. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Receptor   LXR   alpha   Ligand   Binding   Domain   NR1H3   RLD-1   Receptor   LXR   alpha   Ligand   Binding   Domain]  
• Gene symbol
  NR1H3, NR1H2, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR101-1, MIR1289-1, MIR16-1
• Short name
  Receptor LXR alpha, Ligand Binding Domain (NR1H3, RLD-1)[ Receptor LXR alpha, Ligand Binding Domain]
• Host
  Mouse
• Alternative name
  Nuclear Receptor LXR a, Ligand Binding Domain (nuclear receptor subfamily 1, group H, member 3, RLD-1)[Nuclear Receptor LXR a, Ligand Binding Domain]
• Alternative to gene target
  nuclear receptor subfamily 1, group H, member 3, LXR-a and LXRA and RLD-1, NR1H3 and IDBG-42877 and ENSG00000025434 and 10062, transcription regulatory region DNA binding, nuclei, Nr1h3 and IDBG-190792 and ENSMUSG00000002108 and 22259, NR1H3 and IDBG-637355 and ENSBTAG00000010681 and 507176

Gene info

• Identity
  HGNC:7966
• Gene
  NR1H3
• Long gene name
  nuclear receptor subfamily 1 group H member 3
• Synonyms gene name
  • nuclear receptor subfamily 1, group H, member 3
• Synonyms
  • LXR-a
  • RLD-1
  • LXRa
• Synonyms name
  • liver X receptor-alpha
• GenBank acession
  • U22662
• Locus
  11p11.2
• Discovery year
  1999-09-17
• Entrez gene record
  10062
• Pubmed identfication
  • 8621574
  • 7744246
• Classification
  • Nuclear receptor subfamily 1 group H
• VEGA ID
  OTTHUMG00000150628

Gene info

• Identity
  HGNC:7965
• Gene
  NR1H2
• Long gene name
  nuclear receptor subfamily 1 group H member 2
• Synonyms gene
  • UNR
• Synonyms gene name
  • ubiquitously-expressed nuclear receptor
  • nuclear receptor subfamily 1, group H, member 2
• Synonyms
  • NER
  • NER-I
  • RIP15
  • LXR-b
  • LXRb
• Synonyms name
  • liver X receptor-beta
• GenBank acession
  • U14534
• Locus
  19q13.3
• Discovery year
  1994-09-19
• Entrez gene record
  7376
• Pubmed identfication
  • 7782080
  • 7971966
• Classification
  • Nuclear receptor subfamily 1 group H
• VEGA ID
  OTTHUMG00000183036

Gene info

• Identity
  HGNC:5670
• Gene
  IGHVII-1-1
• Long gene name
  immunoglobulin heavy variable (II)-1-1 (pseudogene)
• Synonyms gene name
  • immunoglobulin heavy variable (II)-1-1
  • immunoglobulin heavy variable (II)-1-1 pseudogene
• Synonyms
  • IGHV(II)-1-1
• GenBank acession
  • AB019441
• Locus
  14q32.33
• Discovery year
  2000-04-17
• Entrez gene record
  28377
• RefSeq identity
  • NG_001019
• Classification
  • Immunoglobulin heavy locus at 14q32.33
• VEGA ID
  OTTHUMG00000152325

Gene info

• Identity
  HGNC:31499
• Gene
  MIR1-1
• Long gene name
  microRNA 1-1
• Synonyms gene
  • MIRN1-1
• Synonyms
  • hsa-mir-1-1
• Locus
  20q13.33
• Discovery year
  2004-04-23
• Entrez gene record
  406904
• RefSeq identity
  • NR_029780
• Classification
  • MicroRNA MIR1/206 family

Gene info

• Identity
  HGNC:50820
• Gene
  TRUND-NNN8-1
• Long gene name
  tRNA-undetermined (NNN) 8-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 8-1
• GenBank acession
  • HG984097
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482528
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:50819
• Gene
  TRUND-NNN7-1
• Long gene name
  tRNA-undetermined (NNN) 7-1
• Synonyms gene name
  • transfer RNA-undetermined (NNN) 7-1
• GenBank acession
  • HG984096
• Locus
  1
• Discovery year
  2014-06-20
• Entrez gene record
  103482531
• Pubmed identfication
  • 18984615

Gene info

• Identity
  HGNC:5760
• Gene
  IGKV1OR2-1
• Long gene name
  immunoglobulin kappa variable 1/OR2-1 (pseudogene)
• Synonyms gene
  • IGKVPZ1
  • IGKV1OR-1
• Synonyms gene name
  • immunoglobulin kappa variable 1/OR-1
  • immunoglobulin kappa variable 1/OR-1 pseudogene
  • immunoglobulin kappa variable 1/OR-1 (pseudogene)
• Synonyms
  • IGKV1/OR-1
  • IGKV1/OR2-1
• GenBank acession
  • Z12367
• Locus
  2p11.1
• Discovery year
  2000-04-18
• Entrez gene record
  3531
• Pubmed identfication
  • 2853098
• Classification
  • Immunoglobulin kappa (IGK) orphons
• VEGA ID
  OTTHUMG00000155081

Gene info

• Identity
  HGNC:31488
• Gene
  MIR101-1
• Long gene name
  microRNA 101-1
• Synonyms gene
  • MIRN101-1
• Synonyms
  • hsa-mir-101-1
• Locus
  1p31.3
• Discovery year
  2004-04-23
• Entrez gene record
  406893
• RefSeq identity
  • NR_029516
• Classification
  • MicroRNA MIR101 family

Gene info

• Identity
  HGNC:35281
• Gene
  MIR1289-1
• Long gene name
  microRNA 1289-1
• Synonyms gene
  • MIRN1289-1
• Synonyms
  • hsa-mir-1289-1
• Locus
  20q11.22
• Discovery year
  2008-11-03
• Entrez gene record
  100302125
• RefSeq identity
  • NR_031620
• Classification
  • MicroRNA MIR1289 family

Gene info

• Identity
  HGNC:31545
• Gene
  MIR16-1
• Long gene name
  microRNA 16-1
• Synonyms gene
  • MIRN16-1
• Synonyms
  • hsa-mir-16-1
• Locus
  13q14.2
• Discovery year
  2004-04-23
• Entrez gene record
  406950
• RefSeq identity
  • NR_029486
• Classification
  • MicroRNA MIR15/16 family

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