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Products_type
Antibody
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Products_short_name
[Nuclear Receptor LXR alpha, beta]
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Products_name_syn
[Anti -Nuclear Receptor LXR alpha, beta (Liver X Receptor alpha, Liver X Receptor beta, LX Receptor alpha, LX receptor beta, LXRa, LXRalpha, LXRb, LXRbeta, NERI, NR1H2, NR1H3, Nuclear Orphan Receptor LXR alpha, Nuclear Orphan Receptor LXR beta, Nuclear Receptor]
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Other_names
[NAD-dependent protein deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; NAD-dependent protein deacetylase sirtuin-1; hSIR2; hSIRT1; SIR2alpha; sir2-like 1; sirtuin type 1; SIR2-like protein 1; regulatory protein SIR2 homolog 1; NAD-dependent deacetylase sirtuin-1; sirtuin 1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1]
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Other_gene_names
[SIRT1; SIRT1; SIR2L1; SIR2L1; hSIRT1; hSIR2; 75SirT1]
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Clonality
Polyclonal
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Reactivity
Human, Mouse, Rat
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Specificity
Recognizes human LXR alpha and beta. Species Crossreactivity: mouse, rat.
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Purity
Affinity Purified Purified by immunoaffinity chromatography.
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Form
Supplied as a lyophilized powder from PBS, pH 7.4, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with sterile dH2O.
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Storage_stability
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Western Blot (WB)
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Description
The Receptor LXR alpha, beta (Liver X Receptor alpha, Liver X Receptor beta, LX Receptor alpha, LX receptor beta, LXRa, LXRalpha, LXRb, LXRbeta, NERI, NR1H2, NR1H3, Orphan Receptor LXR alpha, Orphan Receptor LXR beta, Receptor is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
NR1H3, NR1H2
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Short name
Receptor LXR alpha, beta (Liver X Receptor alpha, Liver X Receptor beta, LX Receptor alpha, LX receptor beta, LXRa, LXRalpha, LXRb, LXRbeta, NERI, NR1H2, NR1H3, Orphan Receptor LXR alpha, Orphan Receptor LXR beta, Receptor
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Host
Rabbit
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Isotype
IgG
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Alternative name
Nuclear Receptor LXR a, b (Liver X Receptor a, Liver X Receptor b, LX Receptor a, LX receptor b, LXRa, LXRalpha, LXRb, LXRbeta, NERI, nuclear receptor subfamily 1, group H, member 2, nuclear receptor subfamily 1, group H, member 3, Nuclear Orphan Receptor LXR a, Nuclear Orphan Receptor LXR b, Nuclear Receptor
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Alternative to gene target
nuclear receptor subfamily 1, group H, member 3, LXR-a and LXRA and RLD-1, NR1H3 and IDBG-42877 and ENSG00000025434 and 10062, transcription regulatory region DNA binding, nuclei, Nr1h3 and IDBG-190792 and ENSMUSG00000002108 and 22259, NR1H3 and IDBG-637355 and ENSBTAG00000010681 and 507176
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Tissue
liver
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