NRBP, NT (Nuclear Receptor Binding Protein, Nrbp1, BCON3, FLJ27109, FLJ35541, HLS7-interacting Protein Kinase, Multiple Domain Putative Nuclear Protein, MUDPNP, Myeloid Leukemia Factor 1 Adaptor Molecule, MLF1 Adapter Molecule, MADM)

• Catalog number
  MBS624903
• Price
  Please ask
• Size
  5x0.2 mL

• Products_type
  Antibody
• Products_short_name
  [NRBP]
• Products_name_syn
  [Anti -NRBP, NT (Nuclear Receptor Binding Protein, Nrbp1, BCON3, FLJ27109, FLJ35541, HLS7-interacting Protein Kinase, Multiple Domain Putative Nuclear Protein, MUDPNP, Myeloid Leukemia Factor 1 Adaptor Molecule, MLF1 Adapter Molecule, MADM)]
• Other_names
  [nuclear receptor-binding protein; Nuclear receptor-binding protein; nuclear receptor-binding protein; OTTHUMP00000123427; OTTHUMP00000123428; OTTHUMP00000200794; multiple domain putative nuclear protein; myeloid leukemia factor 1 adaptor molecule; nuclear receptor binding protein 1]
• Other_gene_names
  [NRBP1; NRBP1; MADM; NRBP; BCON3; MUDPNP; FLJ27109; FLJ35541; BCON3; NRBP]
• Clonality
  Polyclonal
• Reactivity
  Human, Mouse
• Specificity
  Recognizes human NRBP. Species Crossreactivity: mouse.
• Purity
  Affinity Purified Purified by Protein G affinity chromatography.
• Form
  Supplied as a liquid in PBS, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Whole adhesion and interacting molecules are  present in lysates used as reference for ELISA quantification of these molecules and their subunits. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  NRBP   Receptor   Binding   Protein   Nrbp1   BCON3   FLJ27109   FLJ35541   HLS7-interacting   Protein   Kinase   Multiple   Domain   Putative   Protein   MUDPNP   Myeloid   Leukemia   Factor   Adaptor   Molecule   MLF1   Adapter   Molecule   MADM  
• Gene symbol
  NRBP1, MLF1, MLF1-DT, ADAM10
• Short name
  NRBP, NT ( Receptor Binding Protein, Nrbp1, BCON3, FLJ27109, FLJ35541, HLS7-interacting Protein Kinase, Multiple Domain Putative Protein, MUDPNP, Myeloid Leukemia Factor 1 Adaptor Molecule, MLF1 Adapter Molecule, MADM)
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  NRBP, NT (Nuclear Receptor Binding Protein, Nrbp1, BCON3, FLJ27109, FLJ35541, HLS7-interacting Protein phosphorylation catalyst, Multiple Domain Putative Nuclear Protein, MUDPNP, Myeloid Leukemia Factor 1 Adaptor Molecule, myeloid leukemia factor 1 Adapter Molecule, MADM)
• Alternative to gene target
  myeloid leukemia factor 1, MLF1 and IDBG-63091 and ENSG00000178053 and 4291, protein domain specific binding, nuclei, Mlf1 and IDBG-150128 and ENSMUSG00000048416 and 17349, MLF1 and IDBG-637188 and ENSBTAG00000004126 and 533379
• Virus
  leukemia

Gene info

• Identity
  HGNC:7993
• Gene
  NRBP1
• Long gene name
  nuclear receptor binding protein 1
• Synonyms gene
  • NRBP
• Synonyms gene name
  • nuclear receptor binding protein
• Synonyms
  • BCON3
  • MUDPNP
  • MADM
• GenBank acession
  • AF113249
• Locus
  2p23.3
• Discovery year
  2000-02-18
• Entrez gene record
  29959
• Pubmed identfication
  • 10843813
  • 11956649
• RefSeq identity
  • NM_013392
• VEGA ID
  OTTHUMG00000097789

Gene info

• Identity
  HGNC:7125
• Gene
  MLF1
• Long gene name
  myeloid leukemia factor 1
• Synonyms name
  • myeloid leukemia factor 1 variant 1
  • myeloid leukemia factor 1 variant 2
  • myeloid leukemia factor 1 variant 3
• GenBank acession
  • L49054
• Locus
  3q25.32
• Discovery year
  1994-08-29
• Entrez gene record
  4291
• Pubmed identfication
  • 8570204
  • 28137643
• RefSeq identity
  • NM_022443
• VEGA ID
  OTTHUMG00000158775
• Locus Specific Databases
  • LRG_1388

Gene info

• Identity
  HGNC:55620
• Gene
  MLF1-DT
• Long gene name
  MLF1 divergent transcript
• Locus
  3q25.32
• Discovery year
  2021-06-21
• Entrez gene record
  100996447
• RefSeq identity
  • NR_104147
• Classification
  • Divergent transcripts

Gene info

• Identity
  HGNC:188
• Gene
  ADAM10
• Long gene name
  ADAM metallopeptidase domain 10
• Synonyms gene name
  • a disintegrin and metalloproteinase domain 10
• Synonyms
  • kuz
  • MADM
  • HsT18717
  • CD156C
• GenBank acession
  • AF009615
• Locus
  15q21.3
• Discovery year
  1997-03-21
• Entrez gene record
  102
• Pubmed identfication
  • 9344679
  • 9441766
• RefSeq identity
  • NM_001110
• Classification
  • ADAM metallopeptidase domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000132633

MeSH Data

• Name
  Leukemia, Experimental
• Concept
  Scope note: Leukemia induced experimentally in animals by exposure to leukemogenic agents, such as VIRUSES; RADIATION; or by TRANSPLANTATION of leukemic tissues.
• Tree numbers
  • C04.557.337.372
  • C04.619.531
  • E05.598.500.496.500
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, rehabilitation, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, psychology, urine, virology, history, classification, economics, embryology, genetics, nursing, radiotherapy, ethnology, prevention & control, pathology, metabolism, complications, surgery

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