NOT1 (NURR1, Cys4 Zinc Finger Nuclear Receptor Type Family Transcription Factor)[NOT1]

• Catalog number
  MBS613153
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human, Rodent
• Description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells. Finger like and finger proteins are like zinc fingers small proteins with a structural motif that is characterized by the coordination of one or more zinc ions in order to stabilize the fold. Homeobox and homeodomain families. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels. The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.

• Gene target
  NOT1   NURR1   Cys4   Zinc   Finger   Receptor   Family   Transcription   Factor   [NOT1]  
• Gene symbol
  CNOT1, NR4A2
• Short name
  NOT1 (NURR1, Cys4 Zinc Finger Receptor Family Transcription Factor)[NOT1]
• Host
  Rabbit
• Alternative name
  NOT1 (NURR1, Cys4 Zinc Finger Nuclear Receptor classification family Transcription Factor)[NOT1]

Gene info

• Identity
  HGNC:7877
• Gene
  CNOT1
• Long gene name
  CCR4-NOT transcription complex subunit 1
• Synonyms gene
  • NOT1
• Synonyms gene name
  • CCR4-NOT transcription complex, subunit 1
• Synonyms
  • CDC39
  • NOT1H
  • KIAA1007
  • AD-005
• GenBank acession
  • AL833549
• Locus
  16q21
• Discovery year
  1996-07-19
• Entrez gene record
  23019
• Pubmed identfication
  • 14702039
• RefSeq identity
  • NM_016284
• Classification
  • Small nucleolar RNA protein coding host genes
  • CCR4-NOT transcription complex
  • Armadillo like helical domain containing
• VEGA ID
  OTTHUMG00000133487

Gene info

• Identity
  HGNC:7981
• Gene
  NR4A2
• Long gene name
  nuclear receptor subfamily 4 group A member 2
• Synonyms gene
  • NURR1
• Synonyms gene name
  • nuclear receptor subfamily 4, group A, member 2
• Synonyms
  • TINUR
  • NOT
  • RNR1
  • HZF-3
• GenBank acession
  • X75918
• Locus
  2q22-q23
• Discovery year
  1997-07-11
• Pubmed identfication
  • 7706727
• Classification
  • Nuclear receptor subfamily 4 group A
• VEGA ID
  OTTHUMG00000131950

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