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Products_type
Antibody
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Products_short_name
[Nogo 66 Receptor]
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Products_name_syn
[Anti -Nogo 66 Receptor (Ngr)]
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Other_names
[NOGO-66 receptor]
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Clonality
Monoclonal
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Clone
[8H116]
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Reactivity
Mouse
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Specificity
Recognizes mouse NgR. In direct ELISAs and Western Blots this antibody does not crossreact with rhNgR.
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Purity
Affinity Purified Purified by Protein G affinity chromatography.
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Form
Supplied as a lyophilized powder in PBS, 5% trehalose. Reconstitution: Reconstitute with sterile PBS. If 1ml of PBS is used, the antibody concentration will be 500ug/ml.
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Storage_stability
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
ELISA (EL/EIA), Western Blot (WB)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
