NKR2B4 (Natural Killer Cell Receptor 2B4, NK Cell Type I Receptor Protein 2B4, 2B4, CD244 Molecule Natural Killer Cell Receptor 2B4, h2B4, CD244, NK Cell Activation Inducing Ligand, NAIL, Nmrk, SLAMF4)
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Catalog number
MBS609436
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Price
Please ask
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Size
0.5 mg
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Products_type
Antibody
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Products_short_name
[NKR2B4]
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Products_name_syn
[Anti -NKR2B4 (Natural Killer Cell Receptor 2B4, NK Cell Type I Receptor Protein 2B4, 2B4, CD244 Molecule Natural Killer Cell Receptor 2B4, h2B4, CD244, NK Cell Activation Inducing Ligand, NAIL, Nmrk, SLAMF4)]
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Other_names
[natural killer cell receptor 2B4 isoform 3; Natural killer cell receptor 2B4; natural killer cell receptor 2B4; h2B4; OTTHUMP00000027884; OTTHUMP00000027885; OTTHUMP00000027886; OTTHUMP00000027887; NK cell activation-inducing ligand; NK cell type I receptor protein 2B4; NK cell activation inducing ligand NAIL; CD244 molecule, natural killer cell receptor 2B4]
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Other_gene_names
[CD244; 2B4; NAIL; Nmrk; NKR2B4; SLAMF4]
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Clonality
Monoclonal
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Clone
[10B1117]
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Reactivity
Human
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Specificity
Recognizes human natural killer receptor 2B4 (NKR2B4).
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Purity
Affinity Purified Purified by Protein G affinity chromatography.
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Form
Supplied as a liquid in PBS, pH 7.4. No preservative added.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Immunoprecipitation (IP), Flow Cytometry (FC/FACS)
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Description
For cells, cell lines and tissues in culture till half confluency. FAS ligand and other ligands are binding to the receptor for signaling pathways for example in apoptosis or JNK signaling. Receptor agonists are often tested for drug development. Whole adhesion and interacting molecules are present in lysates used as reference for ELISA quantification of these molecules and their subunits. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
CD244, GSTT1-AS1
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Short name
NKR2B4 (Natural Killer Receptor 2B4, NK I Receptor Protein 2B4, 2B4, CD244 Molecule Natural Killer Receptor 2B4, h2B4, CD244, NK Activation Ligand, NAIL, Nmrk, SLAMF4)
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Technique
activation
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Host
Mouse
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Isotype
IgG1
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Alternative name
NKR2B4 (Natural Killer cellular Receptor 2B4, NK cellular classification I Receptor Protein 2B4, 2B4, CD244 molecule, natural killer cellular receptor 2B4 Molecule Natural Killer cellular Receptor 2B4, h2B4, CD244 molecule, natural killer cellular receptor 2B4, NK cellular Activation Inducing Ligand, NAIL, Nmrk, SLAMF4)
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Alternative to gene target
CD244 molecule, natural killer cell receptor 2B4, CD244 and IDBG-104114 and ENSG00000122223 and 51744, protein binding, Cell surfaces, Cd244 and IDBG-204694 and ENSMUSG00000004709 and 18106, CD244 and IDBG-630400 and ENSBTAG00000002951 and 513468
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Tissue
cell
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Gene info
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Identity
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Gene
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Long gene name
CD244 molecule
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Synonyms gene name
- natural killer cell receptor 2B4
- CD244 natural killer cell receptor 2B4
- CD244 molecule, natural killer cell receptor 2B4
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Synonyms
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GenBank acession
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Locus
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Discovery year
2003-10-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Ig-like cell adhesion molecule family
- Immunoglobulin like domain containing
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene name
GSTT1 antisense RNA 1
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Synonyms
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GenBank acession
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Locus
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Discovery year
2015-08-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
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