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Products_type
Antibody
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Products_short_name
[NKp46, Natural Cytotoxicity Receptor]
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Products_name_syn
[Anti -NKp46, Natural Cytotoxicity Receptor (NCR NKp46, CD335, Lymphocyte Antigen 94, Ly94, Natural Cytotoxicity Triggering Receptor 1, NCR1, NCT1, Natural Killer Cell Activating Receptor NKp46, NK Cell Activating Receptor) (PE)]
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Other_names
[natural cytotoxicity triggering receptor 1 isoform a; Natural cytotoxicity triggering receptor 1; natural cytotoxicity triggering receptor 1; NK cell-activating receptor; natural killer cell p46-related protein; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein]
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Other_gene_names
[NCR1; NCR1; LY94; CD335; NKP46; NK-p46; LY94; NK-p46; NKp46; hNKp46]
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Clonality
Monoclonal
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Clone
[10B1431 (AKS1)]
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Reactivity
Bovine, American Bison
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Specificity
Recognizes bovine CD335, also known as NKp46 and Natural cytotoxicity triggering receptor 1.
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Purity
Purified by Protein G affinity chromatography from tissue culture supernatant
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Form
Supplied as a lyophilized powder from PBS, pH 7.4, 1% BSA, 0.09% sodium azide, 5% sucrose. Labeled with R-Phycoerythrin (PE). Reconstitute with 1ml sterile ddH2O.
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Storage_stability
Store product at 4°C before and after reconstitution. DO NOT FREEZE! Lyophilized and reconstituted products are stable for 12 months at 4°C after receipt. Reconstitute lyophilized powder with sterile ddH2O prior to use and store remainder as an undiluted liquid. Caution: PE conjugates are sensitive to light. For maximum recovery of product centrifuge the original vial prior to removing the cap.
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Tested_application
Flow Cytometry (FC/FACS)
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Description
Antigens are peptides or recombinant or native dependent on the production method. For cells, cell lines and tissues in culture till half confluency. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
NCR1, NCRUPAR
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Short name
NKp46, Natural Cytotoxicity Receptor (NCR NKp46, CD335, Lymphocyte Antigen 94, Ly94, Natural Cytotoxicity Triggering Receptor 1, NCR1, NCT1, Natural Killer Activating Receptor NKp46, NK Activating Receptor) (PE)
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Technique
antigen, antigenes
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Host
Mouse
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Isotype
IgG1
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Label
PE
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Alternative name
NKp46, Natural Cytotoxicity Receptor (NCR NKp46, CD335, Lymphocyte protein 94, Ly94, Natural Cytotoxicity Triggering Receptor 1, natural cytotoxicity triggering receptor 1, NCT1, Natural Killer cellular Activating Receptor NKp46, NK cellular Activating Receptor) (peroxidase)
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Alternative technique
antigenes
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Alternative to gene target
natural cytotoxicity triggering receptor 1, CD335 and LY94 and NK-p46 and NKP46, NCR1 and IDBG-69753 and ENSG00000189430 and 9437, receptor signaling protein activity, Plasma membranes, Ncr1 and IDBG-137680 and ENSMUSG00000062524 and 17086, NCR1 and IDBG-641998 and ENSBTAG00000045529 and 369024
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Tissue
cell, lymphocyte
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