Nitric Oxide Synthase (NOS) Inhibitor HP-228 [Nle4-Acetyl, Gln5, D-Phe7, D-Trp9]-a-MSH (4-10) amide
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Catalog numberMBS659228
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PricePlease ask
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Size5x1 mg
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Products_typePeptide
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Products_short_name[Nitric Oxide Synthase]
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Other_names[nitric oxide synthase, partial; Nitric oxide synthase, endothelial; nitric oxide synthase, endothelial; cNOS; EC-NOS; NOSIII; NOS type III; endothelial NOS; constitutive NOS; nitric oxide synthase 3 (endothelial cell); Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III]
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Other_gene_names[NOS3; NOS3; eNOS; ECNOS; cNOS; eNOS; NOSIII]
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PurityHighly Purified~95%. Purified by HPLC.
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FormSupplied as a lyophilized powder.
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Storage_stabilityLyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer._x000B_
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DescriptionN terminal acetylation or CH3CO as epigenetic regulation of Nitric Oxide Synthase (NOS) Inhibitor HP-228 [Nle4- , Gln5, D-Phe7, D-Trp9]-a-MSH (4-10) amide by NATs. Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
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Gene target
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Gene symbolMC1R, MSX2, POMC, DEFA4, HP, NOS2, NOS1, PIRC49, SNORD115-10
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Short nameNitric Oxide Synthase (NOS) Inhibitor HP-228 [Nle4- , Gln5, D-Phe7, D-Trp9]-a-MSH (4-10) amide
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HostSynthetic peptide
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Alternative nameNitric Oxide Synthase (NOS) suppressor HP-228 [Nle4-Acetyl, Gln5, D-Phe7, D-Trp9]-a-MSH (4-10) amide
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Gene info
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Identity
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Gene
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Long gene namemelanocortin 1 receptor
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Synonyms gene name
- melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
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Synonyms
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Synonyms name
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Locus
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Discovery year1993-07-27
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Melanocortin receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemsh homeobox 2
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Synonyms gene
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Synonyms gene name
- msh (Drosophila) homeo box homolog 2
- parietal foramina 1
- msh homeobox homolog 2 (Drosophila)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-05-26
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Entrez gene record
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Pubmed identfication
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Classification
- NKL subclass homeoboxes and pseudogenes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameproopiomelanocortin
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Synonyms
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Synonyms name
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Neuropeptides
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namedefensin alpha 4
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Synonyms gene
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Synonyms gene name
- defensin, alpha 4, corticostatin
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-11-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Defensins, alpha
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namehaptoglobin
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sushi domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenitric oxide synthase 2
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Synonyms gene
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Synonyms gene name
- nitric oxide synthase 2A (inducible, hepatocytes)
- nitric oxide synthase 2, inducible
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-06-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namenitric oxide synthase 1
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Synonyms gene
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Synonyms gene name
- nitric oxide synthase 1 (neuronal)
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Synonyms
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Locus
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Discovery year1992-06-09
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Entrez gene record
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Pubmed identfication
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Classification
- PDZ domain containing
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namepiwi-interacting RNA cluster 49
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Locus
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Discovery year2009-11-05
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Entrez gene record
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Pubmed identfication
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Classification
- Piwi-interacting RNA clusters
Gene info
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Identity
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Gene
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Long gene namesmall nucleolar RNA, C/D box 115-10
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Synonyms
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GenBank acession
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Locus
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Discovery year2007-02-15
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNAs, C/D box