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Products_type
Antibody
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Products_short_name
[Nicotinic Receptor, alpha 7]
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Products_name_syn
[Anti -Nicotinic Receptor, alpha 7]
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Other_names
[neuronal acetylcholine receptor subunit alpha-7 isoform 2; Neuronal acetylcholine receptor subunit alpha-7; neuronal acetylcholine receptor subunit alpha-7; a7 nicotinic acetylcholine receptor; alpha-7 nicotinic cholinergic receptor subunit; alpha 7 neuronal nicotinic acetylcholine receptor; cholinergic receptor, nicotinic, alpha polypeptide 7; neuronal acetylcholine receptor protein, alpha-7 chain; cholinergic receptor, nicotinic, alpha 7 (neuronal)]
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Other_gene_names
[CHRNA7; CHRNA7; NACHRA7; CHRNA7-2; NACHRA7]
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Clonality
Polyclonal
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Specificity
Recognizes Nicotinic alpha7 receptor (493-502) and the reactivity of Nicotinic alpha7 receptor is 85%. Does not react to Nicotinic alpha3 receptor, Nicotinic alpha4 receptor, Nicotinic alpha5 receptor, Nicotinic beta2 receptor, Nicotinic beta3 receptor and Nicotinic beta4 receptor.
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Purity
Highly Purified Purified by precipitation, dialysis and chromatography.
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Form
Supplied as a lyophilized powder. Reconstitution ith 5.0 ml of TBS/Tween-20.
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Storage_stability
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Western Blot (WB)
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Description
The Nicotinic Receptor, alpha 7 is a α- or alpha protein sometimes glycoprotein present in blood. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
