NFkB Repressing Factor (NKRF, ITBA4, NRF)
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Catalog number
MBS603882
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Price
Please ask
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Size
5x0.1 mg
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Products_type
Antibody
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Products_short_name
[NFkB Repressing Factor]
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Products_name_syn
[Anti -NFkB Repressing Factor (NKRF, ITBA4, NRF)]
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Other_names
[NF-kappa-B-repressing factor isoform 2; NF-kappa-B-repressing factor; NF-kappa-B-repressing factor; OTTHUMP00000023906; OTTHUMP00000023907; transcription factor NRF; NFKB repressing factor; Protein ITBA4; Transcription factor NRF]
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Other_gene_names
[NKRF; NKRF; NRF; ITBA4; ITBA4; NRF]
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Clonality
Monoclonal
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Clone
[8J130]
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Reactivity
Human
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Specificity
Recognizes human NFkB Repressing Factor.
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Purity
Affinity Purified Purified by Protein G affinity chromatography.
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Form
Supplied as a liquid in PBS, 1% BSA and 0.05% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Western Blot (WB), Gel Shift Assay (GS/EMSA)
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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Gene
NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection (κ light chains are critical components of immunoglobulins). Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory
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Gene target
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Gene symbol
NKRF, NFE2L2, NFE2L1
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Short name
NFkB Repressing Factor (NKRF, ITBA4, NRF)
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Host
Mouse
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Isotype
IgG2b
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Alternative name
NFkB Repressing Factor (NKRF, ITBA4, NRF)
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Gene info
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Identity
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Gene
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Long gene name
NFKB repressing factor
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Synonyms gene name
- NF-kappaB repressing factor
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Synonyms
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GenBank acession
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Locus
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Discovery year
2004-11-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G-patch domain containing
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VEGA ID
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Locus Specific Databases
Gene info
Gene info
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