Neurofilament H, 180-220kD (NF-H))

Products_type

Antibody
Products_short_name

[Neurofilament H, 180-220kD]
Products_name_syn

[Anti -Neurofilament H, 180-220kD (NF-H))]
Clonality

Monoclonal
Clone

[2Q188]
Reactivity

Bovine, Human, Mouse, Rat
Specificity

Recognizes rat Neurofilament H. Reacts with an epitope present on human neurofilaments 200kD and both bovine 160kD and 200kD neurofilaments. Reacts with numerous neurites in human senile plaques and decorates neurofibrillary tangles (NFT) (i.e. on the pyramidal cells of the hippocampus and on neurons of the cerebral cortex of subjects with senile dementia of the Alzheimer's type). Species Crossreactivity: human, mouse, bovine.
Purity

Affinity Purified Purified by Protein A affinity chromatography.
Form

Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Storage_stability

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Tested_application

Western Blot (WB), Immunohistochemistry (IHC)

Gene target

Neurofilament 180-220kD NF-H
Gene symbol

NEFH, LRRC7, NCAPH, NFE4, NFE2, HLA-H, IGHV3-69-1, NFKB1, FUT1, PIGH
Short name

Neurofilament H, 180-220kD (NF-H))
Host

Mouse
Isotype

IgG1
Alternative name

Neurofilament H, 180-220kD (NF-H))

Identity

HGNC:7737
Gene

NEFH
Long gene name

neurofilament heavy chain
Synonyms gene name
- neurofilament, heavy polypeptide 200kDa
- neurofilament heavy polypeptide
- neurofilament heavy
Synonyms
- NF-H
- NFH
Locus

22q12.2
Discovery year

1988-08-31
Entrez gene record

4744
RefSeq identity
- NM_021076
Classification
- Intermediate filaments Type IV
VEGA ID

OTTHUMG00000151155
Locus Specific Databases
- ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database

Identity

HGNC:1112
Gene

NCAPH
Long gene name

non-SMC condensin I complex subunit H
Synonyms gene
- BRRN1
Synonyms gene name
- barren (Drosophila) homolog
- barren homolog (Drosophila)
- barren homolog 1 (Drosophila)
- non-SMC condensin I complex, subunit H
Synonyms
- CAP-H
- hCAP-H
GenBank acession
- BC024211
Locus

2q11.2
Discovery year

1998-02-11
Entrez gene record

23397
Pubmed identfication
- 9417923
RefSeq identity
- NM_015341
Classification
- Condensin I subunits
- Kleisins
VEGA ID

OTTHUMG00000130451

Identity

HGNC:7780
Gene

NFE2
Long gene name

nuclear factor, erythroid 2
Synonyms gene name
- nuclear factor (erythroid-derived 2), 45kD
- nuclear factor (erythroid-derived 2), 45kDa
Synonyms
- NF-E2
GenBank acession
- BC005044
Locus

12q13.13
Discovery year

1993-11-03
Entrez gene record

4778
Pubmed identfication
- 8355703
RefSeq identity
- NM_006163
Classification
- Basic leucine zipper proteins
VEGA ID

OTTHUMG00000169761

Identity

HGNC:5631
Gene

IGHV3-69-1
Long gene name

immunoglobulin heavy variable 3-69-1 (pseudogene)
Synonyms gene
- IGHV3-H
Synonyms gene name
- immunoglobulin heavy variable 3-H (provisional)
- immunoglobulin heavy variable 3-H pseudogene (provisional)
- immunoglobulin heavy variable 3-H (pseudogene)
Synonyms
- IGHV3-h
GenBank acession
- AJ879484
Locus

14q32.33
Discovery year

2000-04-04
Entrez gene record

28402
Pubmed identfication
- 16133446
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000191145

Identity

HGNC:7794
Gene

NFKB1
Long gene name

nuclear factor kappa B subunit 1
Synonyms gene name
- nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
Synonyms
- KBF1
- p105
- NFKB-p50
- p50
- NF-kappaB
- NFkappaB
- NF-kB1
Synonyms name
- Nuclear factor NF-kappa-B p105 subunit
GenBank acession
- M58603
Locus

4q24
Discovery year

1991-11-14
Entrez gene record

4790
Pubmed identfication
- 1992489
RefSeq identity
- NM_003998
Classification
- NF-kappa B complex subunits
- Ankyrin repeat domain containing
- IPT domain containing
VEGA ID

OTTHUMG00000161080
Locus Specific Databases
- LRG_1316

Identity

HGNC:4012
Gene

FUT1
Long gene name

fucosyltransferase 1 (H blood group)
Synonyms gene
- H
- HSC
Synonyms gene name
- fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, Bombay phenotype included)
- fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase)
Synonyms name
- galactoside 2-alpha-L-fucosyltransferase
Locus

19q13.33
Discovery year

1989-06-06
Entrez gene record

2523
RefSeq identity
- NM_000148
Classification
- Fucosyltransferases
- Blood group antigens
VEGA ID

OTTHUMG00000183325
Locus Specific Databases
- Blood Group Antigen Mutation Database
- LRG_810