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Products_type
Antibody
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Products_short_name
[Neurite Outgrowth Inhibitor A]
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Products_name_syn
[Anti -Neurite Outgrowth Inhibitor A (NogoA)]
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Other_names
[neurite outgrowth inhibitor NOGO-A; Neurite outgrowth inhibitor NOGO-A; reticulon-4; neurite outgrowth inhibitor; reticulon 4]
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Other_gene_names
[RTN4; NOGO; NOGO; NOGO-A; RTN4]
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Clonality
Polyclonal
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Reactivity
Rat
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Specificity
Specific for rat Nogo-A. On Western blots for rat brain homogenates, it identifies a band at ~190kD. The faint bands at lower molecular weights may represent the deglycosylated form(s) or degradation product(s) of rat Nogo-A. Reactivity has been confirmed with rat brain homogenates. Based on amino acid sequence homolog, cross-reactivity with
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Purity
Purified Purified by epitope affinity chromatography.
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Form
Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
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Storage_stability
May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Western Blot (WB), Immunoprecipitation (IP)
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Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
