Myosin Regulatory Light Chain Interacting Protein (MYLIP, MIR, BM-023, BZF1, E3 Ubiquitin-protein Ligase MYLIP, Inducible Degrader of the LDL-receptor, IDOL, PP5242)

• Catalog number
  MBS627035
• Price
  Please ask
• Size
  0.2 mL

• Products_type
  Antibody
• Products_short_name
  [Myosin Regulatory Light Chain Interacting Protein]
• Products_name_syn
  [Anti -Myosin Regulatory Light Chain Interacting Protein (MYLIP, MIR, BM-023, BZF1, E3 Ubiquitin-protein Ligase MYLIP, Inducible Degrader of the LDL-receptor, IDOL, PP5242)]
• Other_names
  [myosin regulatory light chain interacting protein; Myosin regulatory light chain interacting protein]
• Other_gene_names
  [MYLIP]
• Clonality
  Polyclonal
• Reactivity
  Human
• Specificity
  Recognizes human MYLIP.
• Purity
  Purified Purified by ammonium sulfate precipitation.
• Form
  Supplied as a liquid in PBS, 0.09% sodium azide.
• Storage_stability
  May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested_application
  ELISA (EL/EIA), Western Blot (WB)
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  Myosin   Regulatory   Light   Chain   Interacting   Protein   MYLIP   MIR   BM-023   BZF1   Ubiquitin-protein   Ligase   MYLIP   Degrader   the   LDL-receptor   IDOL   PP5242  
• Gene symbol
  MYLIP, PLA2G7, SPARC, PHF21A, ZNF644, EIF4A2, EXOC1, RSRC1, SPG21, CYRIB
• Short name
  Myosin Regulatory Light Chain Interacting Protein (MYLIP, MIR, BM-023, BZF1, E3 Ubiquitin-protein Ligase MYLIP, Degrader of the LDL-receptor, IDOL, PP5242)
• Technique
  light
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  Myosin Regulatory Light epitope Interacting Protein (MYLIP, MIR, BM-023, BZF1, E3 Ubiquitin-protein Ligase MYLIP, Inducible Degrader on the LDL-receptor, IDOL, PP5242)

Gene info

• Identity
  HGNC:21155
• Gene
  MYLIP
• Long gene name
  myosin regulatory light chain interacting protein
• Synonyms
  • MIR
  • IDOL
• Synonyms name
  • E3 ubiquitin ligase-inducible degrader of the low density lipoprotein receptor
• GenBank acession
  • AF187016
• Locus
  6p22.3
• Discovery year
  2003-11-26
• Entrez gene record
  29116
• Pubmed identfication
  • 10593918
  • 11162443
  • 19688294
• RefSeq identity
  • NM_013262
• Classification
  • MicroRNA protein coding host genes
  • Ring finger proteins
  • FERM domain containing
• VEGA ID
  OTTHUMG00000016405

Gene info

• Identity
  HGNC:9040
• Gene
  PLA2G7
• Long gene name
  phospholipase A2 group VII
• Synonyms gene name
  • phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
• Synonyms
  • PAFAH
  • LDL-PLA2
• GenBank acession
  • U20157
• Locus
  6p12.3
• Discovery year
  1999-09-20
• Entrez gene record
  7941
• Pubmed identfication
  • 7700381
  • 8624782
• Classification
  • Phospholipases
• VEGA ID
  OTTHUMG00000014789

Gene info

• Identity
  HGNC:11219
• Gene
  SPARC
• Long gene name
  secreted protein acidic and cysteine rich
• Synonyms gene
  • ON
• Synonyms gene name
  • osteonectin
• Synonyms
  • ONT
  • BM-40
• Synonyms name
  • cysteine-rich protein
  • secreted protein acidic and rich in cysteine
• Locus
  5q33.1
• Discovery year
  2001-06-22
• Entrez gene record
  6678
• Pubmed identfication
  • 2838412
  • 3410046
• RefSeq identity
  • NM_003118
• Classification
  • SPARC family
• VEGA ID
  OTTHUMG00000130122

Gene info

• Identity
  HGNC:24156
• Gene
  PHF21A
• Long gene name
  PHD finger protein 21A
• Synonyms
  • BHC80
  • KIAA1696
  • BM-006
• GenBank acession
  • AL359593
• Locus
  11p11.2
• Discovery year
  2005-02-07
• Entrez gene record
  51317
• Pubmed identfication
  • 11214970
  • 12032298
• RefSeq identity
  • NM_016621
• Classification
  • PHD finger proteins
• VEGA ID
  OTTHUMG00000167038

Gene info

• Identity
  HGNC:29222
• Gene
  ZNF644
• Long gene name
  zinc finger protein 644
• Synonyms
  • KIAA1221
  • BM-005
  • MGC60165
  • MGC70410
• GenBank acession
  • AB033047
• Locus
  1p22.2
• Discovery year
  2004-11-08
• Entrez gene record
  84146
• Pubmed identfication
  • 10574462
• RefSeq identity
  • NM_032186
• Classification
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000010078

Gene info

• Identity
  HGNC:3284
• Gene
  EIF4A2
• Long gene name
  eukaryotic translation initiation factor 4A2
• Synonyms gene
  • EIF4F
• Synonyms gene name
  • eukaryotic translation initiation factor 4A, isoform 2
• Synonyms
  • DDX2B
  • EIF4A
  • BM-010
• GenBank acession
  • D30655
• Locus
  3q27.3
• Discovery year
  1995-05-10
• Entrez gene record
  1974
• Pubmed identfication
  • 8521730
• RefSeq identity
  • NM_001967
• Classification
  • DEAD-box helicases
  • Small nucleolar RNA protein coding host genes
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000156564

Gene info

• Identity
  HGNC:30380
• Gene
  EXOC1
• Long gene name
  exocyst complex component 1
• Synonyms gene
  • SEC3L1
• Synonyms gene name
  • SEC3-like 1 (S. cerevisiae)
• Synonyms
  • SEC3
  • FLJ10893
  • BM-102
  • Sec3p
• GenBank acession
  • AK027047
• Locus
  4q12
• Discovery year
  2004-01-08
• Entrez gene record
  55763
• Pubmed identfication
  • 11042152
  • 11406615
• RefSeq identity
  • NM_018261
• Classification
  • Exocyst complex
• VEGA ID
  OTTHUMG00000102165

Gene info

• Identity
  HGNC:24152
• Gene
  RSRC1
• Long gene name
  arginine and serine rich coiled-coil 1
• Synonyms gene name
  • arginine/serine-rich coiled-coil 1
• Synonyms
  • MGC12197
  • BM-011
  • SRrp53
  • SFRS21
• Synonyms name
  • splicing factor, arginine/serine-rich 21
• GenBank acession
  • AF208853
• Locus
  3q25.32
• Discovery year
  2005-02-25
• Entrez gene record
  51319
• Pubmed identfication
  • 15798186
  • 19065146
• RefSeq identity
  • NM_016625
• VEGA ID
  OTTHUMG00000158758

Gene info

• Identity
  HGNC:20373
• Gene
  SPG21
• Long gene name
  SPG21 abhydrolase domain containing, maspardin
• Synonyms gene name
  • spastic paraplegia 21 (autosomal recessive, Mast syndrome)
  • SPG21, maspardin
• Synonyms
  • ACP33
  • GL010
  • BM-019
  • MAST
  • ABHD21
• GenBank acession
  • AF208861
• Locus
  15q22.31
• Discovery year
  2004-04-30
• Entrez gene record
  51324
• Pubmed identfication
  • 11113139
  • 14564668
• RefSeq identity
  • NM_016630
• Classification
  • Abhydrolase domain containing
• VEGA ID
  OTTHUMG00000133098

Gene info

• Identity
  HGNC:25216
• Gene
  CYRIB
• Long gene name
  CYFIP related Rac1 interactor B
• Synonyms gene
  • FAM49B
• Synonyms gene name
  • family with sequence similarity 49, member B
  • family with sequence similarity 49 member B
• Synonyms
  • BM-009
  • CYRI-B
  • CYRI
• GenBank acession
  • AF208851
• Locus
  8q24.21
• Discovery year
  2004-08-20
• Entrez gene record
  51571
• Pubmed identfication
  • 29059164
  • 31285585
• RefSeq identity
  • NM_016623
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000164805

MeSH Data

• Name
  Ligase Chain Reaction
• Concept
  Scope note: A DNA amplification technique based upon the ligation of OLIGONUCLEOTIDE PROBES. The probes are designed to exactly match two adjacent sequences of a specific target DNA. The chain reaction is repeated in three steps in the presence of excess probe: (1) heat denaturation of double-stranded DNA, (2) annealing of probes to target DNA, and (3) joining of the probes by thermostable DNA ligase. After the reaction is repeated for 20-30 cycles the production of ligated probe is measured.
• Tree numbers
  • E05.393.620.311
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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