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Products_type
Antibody
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Products_short_name
[Muscarinic Receptor M2, aa225-356]
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Products_name_syn
[Anti -Muscarinic Receptor M2, aa225-356 (Cholinergic Muscarinic Receptor M2, Chrm2, Muscarinic Receptor M2)]
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Other_names
[muscarinic acetylcholine receptor M2 [Homo sapiens]; Muscarinic acetylcholine receptor M2; muscarinic acetylcholine receptor M2; 7TM receptor; OTTHUMP00000208394; OTTHUMP00000208395; muscarinic M2 receptor; cholinergic receptor, muscarinic 2, isoform a; cholinergic receptor, muscarinic 2]
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Other_gene_names
[CHRM2; CHRM2; HM2; FLJ43243; MGC120006; MGC120007; CHRM2]
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Clonality
Polyclonal
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Reactivity
Canine, Human, Mouse, Porcine, Rat
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Specificity
Recognizes human Muscarinic Receptor M2. Species Crossreactivity
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Purity
Affinity Purified Purified by immunoaffinity chromatography.
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Form
Supplied as a lyophilized powder in PBS, pH 7.4, 1% BSA, 5% sucrose, 0.05% sodium azide. Reconstitution: Reconstitute with 50ul sterile, 40-50% glycerol for long term storage at -20 degree C
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Storage_stability
Lyophilized powder may be stored at -20 degree C. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. May be stored at 4 degree C for short-term only. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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Tested_application
Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
