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Products_type
Antibody
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Products_short_name
[MUC5AC (Mucin 5AC / Gastric Mucin)]
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Products_name_syn
[Apomucin Major Airway Glycoprotein, Mucin 5 subtype AC tracheobronchial, Mucin 5 Subtypes A And C, Mucin 5AC oligomeric mucus/gel forming, Tracheobronchial Mucin (TBM)]
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Other_names
[mucin-5AC; Mucin-5AC; mucin-5AC; mucin 5AC, oligomeric mucus/gel-forming; Gastric mucin]
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Products_gene_name
[MUC5AC]
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Other_gene_names
[MUC5AC; MUC5AC; TBM; leB; MUC5; mucin; TBM]
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Clonality
Monoclonal
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Clone
[SPM297]
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Reactivity
Human, Monkey, Rabbit, Cat, Mouse, Rat, Pig, Hedgehog, Chicken. Does not react with Cow
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Specificity
This MAb recognizes the peptide core of gastric mucin M1 (>1,000kDa) (recently identified as Mucin 5AC). Its epitope is destroyed by beta-mercaptoethanol and proteases but not by periodate treatment. Antibody to gastric mucin M1 reacts with the gastric epithelium of normal human gastrointestinal tract as well as with the precancerous and cancerous colon but not with normal adult colon. It also reacts with fetal colonic mucosa. Resurgence of gastric mucin reactivity during colonic carcinogenesis is due to re-expression of the peptide core of gastric (or fetal colonic) mucins.
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Form
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
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Storage_stability
Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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Tested_application
Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
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Properties
If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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French translation
anticorps
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Gene target
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Gene symbol
MUC5AC
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Short name
MUC5AC (Mucin 5AC / Gastric Mucin) Mouse Monoclonal Antibody
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Technique
Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG1, kappa
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Species
Mouse, Mouses
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Alternative name
mucin 5AC, oli this GO meric mucus/electrophoretic matrix-forming (Mucin 5AC / Gastric Mucin) Mouse monoclonal (antibody to-)
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Alternative technique
antibodies, murine
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Alternative to gene target
mucin 5AC, oli this GO meric mucus/gel-forming, leB and MUC5 and TBM, MUC5AC and IDBG-229951 and ENSG00000215182 and 4586, protein binding, multiple, Muc5ac and IDBG-212386 and ENSMUSG00000037974 and 17833, IDBG-645651 and IDBG-645651 and ENSBTAG00000038262 and
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