MT-ND4 shRNA Plasmid (Human)

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Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Kit

Plasmid mini made and maxi DNA purification kits can be silica gel or anion exchange, endotoxin free and are used to produce pure plasmids that are small DNA molecules within a cell separated from chromosomal DNA and can replicate independently. They are most commonly found in bacteria as small circular, double-stranded DNA molecules; however, plasmids are sometimes present in archaea and eukaryotic organisms. In nature, plasmids often carry genes that may benefit the survival of the organism, for example antibiotic resistance. While the chromosomes are big and contain all the essential information for living, plasmids usually are very small and contain only additional information. Artificial plasmids are widely used as vectors in molecular cloning, serving to drive the replication of recombinant DNA sequences within host organisms.

Gene target

MT-ND4 shRNA
Gene symbol

MT-ND4, MT-TFY, MT-HSP1, MT-RNR3, MT-TAS, MT-LSP, MT-TFL, MT-OHR, MT-ATT, MT-HSP2
Short name

MT-ND4 shRNA Plasmid ( )
Technique

plasmid, plasmids in 1
Species

Human, Humans
Alternative name

MT-ND4 short hairpin RNA Plasmid (H. sapiens)
Alternative technique

plasmids

Identity

HGNC:7459
Gene

MT-ND4
Long gene name

mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 4
Synonyms gene
- MTND4
- LHON
Synonyms gene name
- NADH dehydrogenase 4
- Leber optic neuropathy
- mitochondrially encoded NADH dehydrogenase 4
Synonyms
- ND4
- NAD4
Synonyms name
- complex I ND4 subunit
- NADH-ubiquinone oxidoreductase chain 4
Locus

mitochondria
Discovery year

1989-06-03
Entrez gene record

4538
Pubmed identfication
- 8103501
RefSeq identity
- YP_003024035
Classification
- NADH:ubiquinone oxidoreductase core subunits
- Mitochondrially encoded protein coding genes

Identity

HGNC:7476
Gene

MT-TAS
Long gene name

mitochondrially encoded termination associated sequence
Synonyms gene
- MTTAS
Synonyms gene name
- termination associated sequence
- mitochondrially encoded termination associate sequence
Locus

mitochondria
Discovery year

1989-10-11
Pubmed identfication
- 9473475
Classification
- Mitochondrially encoded regions