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Products_type
Antibody
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Products_short_name
[F2 / Prothrombin / Thrombin]
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Products_name_syn
[Anti-F2 / Prothrombin / Thrombin Antibody IHC-plus; F2; Prothrombin B-chain; Coagulation factor II; FACTOR II; Prothrombin; PT; RPRGL2; Serine protease; THPH1; Thrombin; Human F2; Prothrombin; Thrombin]
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Other_names
[prothrombin preproprotein; Prothrombin; prothrombin; serine protease; prothrombin B-chain; prepro-coagulation factor II; coagulation factor II (thrombin); Coagulation factor IICleaved into the following 4 chains:Activation peptide fragment 1; Activation peptide fragment 2; Thrombin light chain; Thrombin heavy chain]
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Products_gene_name
[F2]
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Other_gene_names
[F2; F2; PT; THPH1; RPRGL2]
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Clonality
Monoclonal
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Reactivity
Human
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Specificity
Recognizes human Prothrombin, prethrombin-1, fragment 2, meizothrombin. Inhibits clotting and prothrombin activation.
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Purity
Ion exchange Chromatography
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Form
Supplied as a liquid in 50% glycerol, ddH2O.
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Concentration
1 mg/ml
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Storage_stability
+4 degree C or -20 degree C, Avoid repeated freezing and thawing.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Short name
Mouse Monoclonal (IgG2a) F2 / Prothrombin / Thrombin
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Technique
Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG2a, IgG2a
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Species
Human, Humans, Mouses
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Alternative name
Mouse monoclonal (IgG2a) to H. sapiens coagulation factor II (thrombin) / Prothrombin / Thrombin
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Alternative technique
murine
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Alternative to gene target
coagulation factor II (thrombin), PT and RPRGL2 and THPH1, F2 and IDBG-42048 and ENSG00000180210 and 2147, thrombospondin receptor activity, Extracellular, F2 and IDBG-191373 and ENSMUSG00000027249 and 14061, F2 and IDBG-637247 and ENSBTAG00000007148 and 280685
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