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Products_type
Antibody
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Products_short_name
[FAK / Focal Adhesion Kinase]
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Products_name_syn
[Anti-FAK / Focal Adhesion Kinase Antibody (aa1-423) IHC-plus; FADK; Fadk1; Focal adhesion kinase; FRNK; FADK 1; Focal adhesion kinase 1; FAK1; p125FAK; PPP1R71; Protein-tyrosine kinase 2; PTK2 protein tyrosine kinase 2; pp125 FA kinase; Pp125FAK; Human FAK; Focal Adhesion Kinase]
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Other_names
[focal adhesion kinase 1 isoform b; Focal adhesion kinase 1; focal adhesion kinase 1; FADK 1; PTK2 protein tyrosine kinase 2; FAK-related non-kinase polypeptide; focal adhesion kinase isoform FAK-Del33; focal adhesion kinase-related nonkinase; protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; protein tyrosine kinase 2; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK]
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Products_gene_name
[PTK2]
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Products_gene_name_syn
[FAK]
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Other_gene_names
[PTK2; PTK2; FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK; FAK; FAK1; FADK 1; FRNK; PPP1R71]
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Clonality
Monoclonal
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Reactivity
Human, Mouse, Rat
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Specificity
GST fusion protein corresponding to residues 1-423 of human FAK (focal adhesion kinase)
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Purity
Protein G Purified
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Form
PBS, pH 7.6, 0.175 M sodium chloride, 0.07% sodium azide, 30% glycerol.
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Concentration
1 mg/ml
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Storage_stability
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA)
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Description
cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the Mouse Monoclonal (IgG1) FAK / Focal Adhesion Kinase.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus