Mouse Monoclonal [clone DE-K18] (IgG1) to Human KRT18 / CK18 / Cytokeratin 18

• Catalog number
  MBS246430
• Price
  Please ask
• Size
  0.05 mg

• Products_type
  Antibody
• Products_short_name
  [KRT18 / CK18 / Cytokeratin 18]
• Products_name_syn
  [Anti-KRT18 / CK18 / Cytokeratin 18 Antibody (clone DE-K18) IHC-plus; KRT18; CK-18; Cytokeratin 18; Cytokeratin-18; K18; Keratin 18; CYK18; Keratin-18; Human KRT18; CK18; Cytokeratin 18]
• Other_names
  [keratin, type I cytoskeletal 18; Keratin, type I cytoskeletal 18; keratin, type I cytoskeletal 18; CK-18; keratin-18; cytokeratin 18; cytokeratin-18; cell proliferation-inducing protein 46; cell proliferation-inducing gene 46 protein; keratin 18; Cell proliferation-inducing gene 46 protein; Cytokeratin-18; CK-18; Keratin-18; K18]
• Products_gene_name
  [KRT18]
• Other_gene_names
  [KRT18; KRT18; K18; CYK18; CYK18; CK-18; K18]
• Clonality
  Monoclonal
• Clone
  [DE-K18]
• Reactivity
  Cat, Dog, Human
• Specificity
  Reacts exclusively with cytokeratin 18 which is present in glandular epithelial cells of the digestive, respiratory, and urogenital tracts, endocrine and exocrine cells and mesothelial cells, as well as adenocarcinomas originating from them.
• Purity
  Purified
• Form
  PBS containing 0.09% sodium azide
• Concentration
  1 mg/ml
• Storage_stability
  Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.
• Tested_application
  Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS)
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Monoclonal   DE-K18]   IgG1   KRT18   CK18   Cytokeratin  
• Gene symbol
  KRT18, ERVK-18, DSEL, TRHDE
• Short name
  Mouse Monoclonal [clone DE-K18] (IgG1) KRT18 / CK18 / Cytokeratin 18
• Technique
  Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG1, IgG1
• Species
  Human, Humans, Mouses
• Alternative name
  Mouse monoclonal [clonality DE-K18] (IgG1) to H. sapiens keratin 18 / CK18 / Cytokeratin 18
• Alternative technique
  murine
• Alternative to gene target
  keratin 18, CYK18 and K18, KRT18 and IDBG-35299 and ENSG00000111057 and 3875, scaffold protein binding, nuclei, Krt18 and IDBG-187416 and ENSMUSG00000023043 and 16668, KRT18 and IDBG-631626 and ENSBTAG00000001517 and 506480
• Clone name
  DE-K18

Gene info

• Identity
  HGNC:6430
• Gene
  KRT18
• Long gene name
  keratin 18
• Synonyms gene name
  • keratin 18, type I
• Locus
  12q13.13
• Discovery year
  1988-08-12
• Entrez gene record
  3875
• Pubmed identfication
  • 1705144
  • 16831889
• RefSeq identity
  • NM_199187
• Classification
  • Keratins, type I
• VEGA ID
  OTTHUMG00000169882

Gene info

• Identity
  HGNC:39025
• Gene
  ERVK-18
• Long gene name
  endogenous retrovirus group K member 18
• Synonyms gene name
  • endogenous retrovirus group K, member 18
• Synonyms
  • c1_C
  • HERV-K18
• Synonyms name
  • HERV-K_1q23.3 provirus ancestral Env polyprotein
  • endogenous retrovirus K-18
  • IDDMK1,2-22
  • HERV-K_1q23.3 provirus ancestral Pol protein
  • HERV-K_1q23.3 provirus ancestral Pro protein
• GenBank acession
  • FN806828
  • AF012336
• Locus
  1q23.3
• Discovery year
  2011-05-05
• Pubmed identfication
  • 18664271
  • 10516026
  • 21542922

Gene info

• Identity
  HGNC:18144
• Gene
  DSEL
• Long gene name
  dermatan sulfate epimerase like
• Synonyms gene
  • C18orf4
• Synonyms gene name
  • chromosome 18 open reading frame 4
  • dermatan sulfate epimerase-like
• Synonyms
  • NCAG1
  • FLJ11477
  • DE-epi2
• GenBank acession
  • AF480435
• Locus
  18q22.1
• Discovery year
  2002-02-12
• Entrez gene record
  92126
• Pubmed identfication
  • 16505484
  • 19188366
• RefSeq identity
  • NM_032160
• VEGA ID
  OTTHUMG00000132804

Gene info

• Identity
  HGNC:30748
• Gene
  TRHDE
• Long gene name
  thyrotropin releasing hormone degrading enzyme
• Synonyms gene name
  • thyrotropin-releasing hormone degrading enzyme
• Synonyms
  • PGPEP2
  • TRH-DE
  • PAP-II
• Synonyms name
  • pyroglutamyl-peptidase II
  • pyroglutamyl aminopeptidase II
  • TRH-specific aminopeptidase
• GenBank acession
  • AF126372
• Locus
  12q21.1
• Discovery year
  2005-05-10
• Entrez gene record
  29953
• Pubmed identfication
  • 10491199
  • 12975309
• RefSeq identity
  • NM_013381
• Classification
  • M1 metallopeptidases
• VEGA ID
  OTTHUMG00000169642

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