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Products_type
Antibody
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Products_short_name
[CFH / Complement Factor H]
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Products_name_syn
[Anti-CFH / Complement Factor H Antibody (clone 63G5) IHC-plus; CFH; Adrenomedullin binding protein; AHUS1; AMBP1; ARMS1; ARMD4; Beta-1-H-globulin; Factor H; Factor H-like 1; HF; HF2; H factor 1; H factor 2 (complement); HUS; HF1; Beta-1H; CFHL3; Complement factor H; H factor 1 (complement); Human CFH; Complement Factor H]
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Other_names
[complement factor H isoform a; Complement factor H; complement factor H; beta-1H; factor H-like 1; beta-1-H-globulin; H factor 1 (complement); H factor 2 (complement); adrenomedullin binding protein; complement factor H, isoform b; age-related maculopathy susceptibility 1; complement factor H; H factor 1]
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Products_gene_name
[CFH]
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Other_gene_names
[CFH; CFH; FH; HF; HF1; HF2; HUS; FHL1; AHUS1; AMBP1; ARMD4; ARMS1; CFHL3; HF; HF1; HF2]
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Clonality
Monoclonal
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Clone
[63G5]
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Reactivity
Human
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Purity
Ammonium sulfate precipitation
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Form
HEPES with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol
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Storage_stability
Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Immunoprecipitation (IP), ELISA (EIA)
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Description
Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Gene symbol
CFH
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Short name
Mouse Monoclonal [clone 63G5] (IgG2b k) CFH / Complement Factor H
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Technique
Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG2b,k, IgG2b
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Species
Human, Humans, Mouses
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Alternative name
Mouse monoclonal [clonality 63G5] (IgG2b,k) to H. sapiens complement factor H / Complement Factor H
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Alternative technique
murine
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Alternative to gene target
complement factor H, AHUS1 and AMBP1 and ARMD4 and ARMS1 and CFHL3 and FH and FHL1 and HF and HF1 and HF2 and HUS, CFH and IDBG-105504 and ENSG00000000971 and 3075, heparan sulfate proteoglycan binding, Extracellular
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Clone name
63G5
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