Mouse Monoclonal [clone 3G4] (IgG2b) to Human ERCC3 / XPB
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Catalog number
MBS245886
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Price
Please ask
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Size
0.05 mg
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Products_type
Antibody
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Products_short_name
[ERCC3 / XPB]
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Products_name_syn
[Anti-ERCC3 / XPB Antibody (aa242-261, clone 3G4) IHC-plus; ERCC3; BTF2; GTF2H; RAD25; TFIIH p89; TFIIH; XPB; BTF2 p89; XPBC; TFIIH 89 kDa subunit; Human ERCC3; XPB]
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Other_names
[TFIIH basal transcription factor complex helicase XPB subunit isoform a; TFIIH basal transcription factor complex helicase XPB subunit; TFIIH basal transcription factor complex helicase XPB subunit; BTF2 p89; TFIIH p89; DNA repair helicase; TFIIH 89 kDa subunit; DNA excision repair protein ERCC-3; DNA repair protein complementing XP-B cells; basic transcription factor 2 89 kDa subunit; xeroderma pigmentosum, complementation group B; xeroderma pigmentosum group B-complementing protein; TFIIH basal transcription factor complex 89 kDa subunit; excision repair cross-complementing rodent repair deficiency, complementation group 3; excision repair cross-complementation group 3; Basic transcription factor 2 89 kDa subunit; BTF2 p89; DNA excision repair protein ERCC-3; DNA repair protein complementing XP-B cells; TFIIH basal transcription factor complex 89 kDa subunit; TFIIH 89 kDa subunit; TFIIH p89; Xeroderma pigmentosum group B-complementing protein]
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Products_gene_name
[ERCC3]
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Products_gene_name_syn
[XPB]
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Other_gene_names
[ERCC3; ERCC3; XPB; BTF2; GTF2H; RAD25; TFIIH; XPB; XPBC; BTF2 p89; TFIIH 89 kDa subunit; TFIIH p89]
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Clonality
Monoclonal
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Clone
[3G4]
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Reactivity
Human
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Specificity
Recognizes an epitope located between aa242-261 of ERCC-3 (largest subunit of TFIIH).
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Purity
Protein G Purified
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Form
0.1 M Tris-HCl, pH 7.5.
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Concentration
1 mg/ml
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Storage_stability
Long term: -20 degree C; Short term: +4 degree C. Avoid repeat freeze-thaw cycles.
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Tested_application
Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA)
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Gene target
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Gene symbol
ERCC3
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Short name
Mouse Monoclonal [clone 3G4] (IgG2b) ERCC3 / XPB
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Technique
Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG2b, IgG2b
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Species
Human, Humans, Mouses
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Alternative name
Mouse monoclonal [clonality 3G4] (IgG2b) to H. sapiens excision repair cross-complementing rodent repair deficiency, complementation family 3 / XPB
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Alternative technique
murine
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Alternative to gene target
excision repair cross-complementing rodent repair deficiency, complementation group 3, BTF2 and GTF2H and RAD25 and TFIIH and XPB, ERCC3 and IDBG-68963 and ENSG00000163161 and 2071, protein N-terminus binding, nuclei, Ercc3 and IDBG-133673 and ENSMUSG00000024382 and 13872, ERCC3 and IDBG-639240 and ENSBTAG00000020777 and 507984
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Clone name
3G4
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Gene info
Product images
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