Mouse Monoclonal [clone 3F4-1D9] (IgG2a,k) to Human SERPING1 / C1 Inhibitor

• Catalog number
  MBS246074
• Price
  Please ask
• Size
  0,05 mg

• Other size
  please contact us to order other different size
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Monoclonal   3F4-1D9]   IgG2a   SERPING1   Inhibitor  
• Gene symbol
  SERPING1
• Short name
  Mouse Monoclonal [clone 3F4-1D9] (IgG2a k) SERPING1 / C1 Inhibitor
• Technique
  Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG2a
• Species
  Human, Humans, Mouses
• Alternative name
  Mouse monoclonal [clonality 3F4-1D9] (IgG2a,k) to H. sapiens serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 / C1 suppressor
• Alternative technique
  murine
• Alternative to gene target
  serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, C1IN and C1INH and C1NH and HAE1 and HAE2, SERPING1 and IDBG-46853 and ENSG00000149131 and 710, peptidase activity, Extracellular, Serping1 and IDBG-185264 and ENSMUSG00000023224 and 12258, BT.22969 and IDBG-637881 and ENSBTAG00000016267 and 281035
• Clone name
  3F4-1D9

Gene info

• Identity
  HGNC:1228
• Gene
  SERPING1
• Long gene name
  serpin family G member 1
• Synonyms gene
  • C1NH
• Synonyms gene name
  • serine (or cysteine) proteinase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)
  • serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
• Synonyms
  • C1IN
  • C1-INH
  • HAE1
  • HAE2
  • C1INH
• Synonyms name
  • plasma protease C1 inhibitor
  • angioedema, hereditary
  • C1-inhibitor
• GenBank acession
  • X54486
• Locus
  11q12.1
• Discovery year
  2001-06-22
• Entrez gene record
  710
• Pubmed identfication
  • 2026152
  • 24172014
• RefSeq identity
  • NM_000062
• Classification
  • Complement system regulators and receptors
  • Serpin peptidase inhibitors
• VEGA ID
  OTTHUMG00000150304
• Locus Specific Databases
  • SERPING1base: Mutation registry for Hereditary angioedema
  • LRG_105

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