Mouse Monoclonal [clone 2F4] (IgG2a,k) to Human Vitamin D Receptor / VDR[Vitamin D Receptor / VDR]
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Catalog number
MBS246023
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Price
Please ask
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Size
NA
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Products_type
Antibody
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Products_gene_name
[VDR]
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Reactivity
Human
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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About
Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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Test
Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin name
Mus musculus
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Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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Gene target
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Gene symbol
VDR
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Short name
Mouse Monoclonal [clone 2F4] (IgG2a k) Vitamin D Receptor / VDR[Vitamin D Receptor / VDR]
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Technique
Mouse monoclonal, Mouse, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Host
Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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Isotype
IgG2a
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Species
Human, Humans, Mouses
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Alternative name
Mouse monoclonal [clonality 2F4] (IgG2a,k) to H. sapiens Vitamin D Receptor / vitamin D (1,25- dihydroxyvitamin D3) receptor[Vitamin D Receptor / vitamin D (1,25- dihydroxyvitamin D3) receptor]
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Alternative technique
murine
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Alternative to gene target
vitamin D (1,25- dihydroxyvitamin D3) receptor, NR1I1 and PPP1R163, VDR and IDBG-29237 and ENSG00000111424 and 7421, lithocholic acid binding, nuclei, Vdr and IDBG-179227 and ENSMUSG00000022479 and 22337, VDR and IDBG-633008 and ENSBTAG00000016414 and 533656
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Clone name
2F4
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Gene info
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Identity
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Gene
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Long gene name
vitamin D receptor
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Synonyms gene name
- vitamin D (1,25- dihydroxyvitamin D3) receptor
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1989-06-30
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Entrez gene record
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Pubmed identfication
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Classification
- Protein phosphatase 1 regulatory subunits
- Nuclear receptor subfamily 1 group I
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VEGA ID
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Locus Specific Databases
Product images
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